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Stockholders' Equity (Tables) | 9 Months Ended
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Sep. 30, 2025
Stockholders' Equity Note [Abstract] |
Summary of Stock Option Activity | The following table summarizes the option activity under the 2020 Plan and 2015 Plan during the nine months ended September 30, 2025:
|  | Number of shares |  |  | Weighted average exercise price |  |  | Weighted average remaining contractual term (in years) |  |  | Aggregate Intrinsic Value |
Outstanding at December 31, 2024 |  |  | 9,069,194 |  |  | $ | 10.55 |  |  |  | 7.0 |  |  | $ | 263 |
Granted |  |  | 4,450,219 |  |  |  | 2.12 |  |  |  |  |  |  |
Forfeited |  |  | (2,570,533 | ) |  |  | 5.64 |  |  |  |  |  |  |
Outstanding at September 30, 2025 |  |  | 10,948,880 |  |  | $ | 8.28 |  |  |  | 6.3 |  |  | $ | 668 |
Exercisable at September 30, 2025 |  |  | 6,151,152 |  |  | $ | 12.14 |  |  |  | 4.1 |  |  | $ | 27 |
Vested and expected to vest at September 30, 2025 |  |  | 10,948,880 |  |  | $ | 8.28 |  |  |  | 6.3 |  |  | $ | 668 |
Summary of Restricted Stock Unit Activity | The following table summarizes the restricted stock unit activity under the 2020 Plan during the nine months ended September 30, 2025:
|  | Number of shares |  |  | Weighted average grant date fair value per share |  |  | Weighted average remaining contractual term (in years) |
Outstanding at December 31, 2024 |  |  | 1,167,911 |  |  | $ | 6.71 |  |  |  | 1.4 |
Granted |  |  | 778,078 |  |  |  | 2.50 |  |  |  |
Vested |  |  | (327,242 | ) |  |  | 6.87 |  |  |  |
Forfeited |  |  | (957,111 | ) |  |  | 4.87 |  |  |  |
Outstanding at September 30, 2025 |  |  | 661,636 |  |  | $ | 4.34 |  |  |  | 1.5 |
Summary of Share-based Compensation Expense | Share-based compensation expense for the three and nine months ended September 30, 2025 and 2024 was as follows (in thousands):
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
Research and development |  | $ | 541 |  |  | $ | 1,793 |  |  | $ | 2,532 |  |  | $ | 6,198 |
General and administrative |  |  | 1,232 |  |  |  | 2,262 |  |  |  | 4,128 |  |  |  | 6,639 |
Total share-based compensation |  | $ | 1,773 |  |  | $ | 4,055 |  |  | $ | 6,660 |  |  | $ | 12,837 |

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- Definition Tabular disclosure of cost recognized for award under share-based payment arrangement by plan. Includes, but is not limited to, related tax benefit. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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