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Segment Reporting | 9 Months Ended
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Sep. 30, 2025
Segment Reporting [Abstract] |
Segment Reporting | 11. Segment Reporting The Company operates as a single reporting segment, focused on the research and development of cell therapies for patients with autoimmune diseases. The Company's measure of segment profit or loss is net loss. The Chief Executive Officer, as the CODM, manages and allocates resources to the operations of the Company on a total company basis. The Company monitors its cash, cash equivalents, and investments as reported on the Company's Balance Sheets to determine funding for its research and development. The measure of segment assets is reported on the balance sheets as total assets. As the Company is not yet generating revenue, the CODM evaluates its performance based on progress in pre-clinical and clinical research objectives. Along with the Company’s Statement of Operations and Comprehensive Loss, the CODM regularly reviews budgeted and forecasted expenses to assess liquidity requirements and allocate cash accordingly. The following table is representative of the significant expense categories regularly provided to the CODM when managing the Company's single reporting segment. A reconciliation to the net loss for the three and nine months ended September 30, 2025 and 2024 is included at the bottom of the table below.
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
Segment expenses: |  |  |  |  |  |  |  |  |  |  |  |
Personnel related expenses, excluding share-based compensation(1) |  |  | 8,125 |  |  |  | 10,674 |  |  | $ | 31,739 |  |  | $ | 31,083 |
Facilities expenses |  |  | 5,241 |  |  |  | 4,683 |  |  |  | 14,577 |  |  |  | 14,035 |
Direct external development program expenses |  |  | 4,644 |  |  |  | 5,807 |  |  |  | 14,913 |  |  |  | 16,876 |
Other segment expenses (2) |  |  | 4,406 |  |  |  | 6,228 |  |  |  | 15,420 |  |  |  | 15,576 |
Total segment expenses: |  |  | 22,416 |  |  |  | 27,392 |  |  |  | 76,649 |  |  |  | 77,570 |
Segment loss |  |  | (22,416 | ) |  |  | (27,392 | ) |  |  | (76,649 | ) |  |  | (77,570 | )
Reconciling items: |  |  |  |  |  |  |  |  |  |  |  |
Depreciation and amortization |  |  | (2,306 | ) |  |  | (2,347 | ) |  |  | (6,936 | ) |  |  | (6,864 | )
Share-based compensation |  |  | (1,773 | ) |  |  | (4,055 | ) |  |  | (6,660 | ) |  |  | (12,837 | )
Impairment of right-of-use asset |  |  | (791 | ) |  |  | — |  |  |  | (791 | ) |  |  | — |
Interest income |  |  | 3,852 |  |  |  | 5,453 |  |  |  | 12,198 |  |  |  | 14,423 |
Other income (expense), net |  |  | 1,719 |  |  |  | (3 | ) |  |  | 2,163 |  |  |  | (7 | )
Net loss |  | $ | (21,715 | ) |  | $ | (28,344 | ) |  | $ | (76,675 | ) |  | $ | (82,855 | )
(1) Personnel related expenses include ($0.1) million and $5.0 million of severance and other benefits expense for the three and nine months ended September 30, 2025, respectively. (2) Other segment items include consultants and contractor, lab supplies, and general business expenses.

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- Definition The entire disclosure for reporting segments including data and tables. 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