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Stockholders' Equity | 9 Months Ended
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Sep. 30, 2025
Stockholders' Equity Note [Abstract] |
Stockholders' Equity | 9. Stockholders' Equity Equity Incentive Plan The Company’s 2020 Performance Incentive Plan (the "2020 Plan"), which was adopted by the Company’s board of directors in June 2020 and approved by the Company’s stockholders in July 2020, became effective upon the consummation of the Company’s initial public offering in July 2020 ("IPO"). Upon the effectiveness of the 2020 Plan, no further grants may be made under the Company’s 2015 Equity Incentive Plan (the "2015 Plan"). The 2020 Plan allows for the grant of incentive stock options, non-qualified stock options, stock appreciation rights, stock bonuses, restricted stock, stock units and other forms of awards including cash awards to its officers, directors, employees, consultants and advisors. As of September 30, 2025, a total of 14,380,237 shares of the Company’s common stock were authorized for issuance with respect to awards granted under the 2020 Plan (this number of shares gives effect to the annual increases in the 2020 Plan share limit, as described in the next sentence, through that date). The share limit will automatically increase on the first trading day in January of each year by an amount equal to the lesser of (1) 5% of the total number of outstanding shares of the Company’s common stock on the last trading day in December in the prior year, or (2) such lesser number as determined by the Company’s board of directors. Any shares subject to awards granted under the 2020 Plan or the 2015 Plan that are not paid, delivered or exercised before they expire or are canceled or terminated, or otherwise fail to vest, as well as shares used to pay the purchase or exercise price of such awards or related tax withholding obligations, will become available for new award grants under the 2020 Plan. A total of 3,700,373 shares were available for issuance under the 2020 Plan as of September 30, 2025. The following table summarizes the option activity under the 2020 Plan and 2015 Plan during the nine months ended September 30, 2025:
|  | Number of shares |  |  | Weighted average exercise price |  |  | Weighted average remaining contractual term (in years) |  |  | Aggregate Intrinsic Value |
Outstanding at December 31, 2024 |  |  | 9,069,194 |  |  | $ | 10.55 |  |  |  | 7.0 |  |  | $ | 263 |
Granted |  |  | 4,450,219 |  |  |  | 2.12 |  |  |  |  |  |  |
Forfeited |  |  | (2,570,533 | ) |  |  | 5.64 |  |  |  |  |  |  |
Outstanding at September 30, 2025 |  |  | 10,948,880 |  |  | $ | 8.28 |  |  |  | 6.3 |  |  | $ | 668 |
Exercisable at September 30, 2025 |  |  | 6,151,152 |  |  | $ | 12.14 |  |  |  | 4.1 |  |  | $ | 27 |
Vested and expected to vest at September 30, 2025 |  |  | 10,948,880 |  |  | $ | 8.28 |  |  |  | 6.3 |  |  | $ | 668 |
The weighted average grant date fair value of stock option grants was $1.72 and $5.05 p er share for the nine months ended September 30, 2025 and 2024, respectively. The following table summarizes the restricted stock unit activity under the 2020 Plan during the nine months ended September 30, 2025:
|  | Number of shares |  |  | Weighted average grant date fair value per share |  |  | Weighted average remaining contractual term (in years) |
Outstanding at December 31, 2024 |  |  | 1,167,911 |  |  | $ | 6.71 |  |  |  | 1.4 |
Granted |  |  | 778,078 |  |  |  | 2.50 |  |  |  |
Vested |  |  | (327,242 | ) |  |  | 6.87 |  |  |  |
Forfeited |  |  | (957,111 | ) |  |  | 4.87 |  |  |  |
Outstanding at September 30, 2025 |  |  | 661,636 |  |  | $ | 4.34 |  |  |  | 1.5 |
The weighted average grant date fair value of restricted stock units was $2.50 and $6.04 per share for the nine months ended September 30, 2025 and 2024, respectively. Employee Stock Purchase Plan The Company’s 2020 Employee Stock Purchase Plan (the "ESPP"), which was adopted by the Company’s board of directors in June 2020 and approved by the Company’s stockholders in July 2020, became effective upon the consummation of the IPO. The ESPP allows eligible employees to purchase shares of the Company’s common stock at a discount through payroll deductions of up to 15% of their eligible compensation, subject to any plan limitations. The ESPP provides for six-month offering periods, and at the end of each offering period, employees are able to purchase shares at 85% of the lower of the fair market value of the Company’s common stock on the first trading day of the offering period or on the last trading day of the offering period. The six-month offering periods extend from June to November and December to May. As of September 30, 2025, 2,217,069 shares of the Company’s common stock remained available for issuance under the ESPP (after giving effect to share purchases under the ESPP, and annual increases in the ESPP share limit as described in the next sentence through that date). The number of shares of the Company’s common stock available for issuance under the ESPP automatically increases on the first trading day in January of each year by an amount equal to the lesser of (i) 1% of the total number of outstanding shares of the Company’s common stock issued and outstanding on December 31 of the immediately preceding calendar year, (ii) 1,000,000 shares, or (iii) such lesser number as determined by the Company’s board of directors. As of September 30, 2025, employee contributions to the ESPP were immaterial and included as part of accrued and other current liabilities in the condensed balance sheets. Share-Based Compensation Expense Share-based compensation expense for the three and nine months ended September 30, 2025 and 2024 was as follows (in thousands):
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
Research and development |  | $ | 541 |  |  | $ | 1,793 |  |  | $ | 2,532 |  |  | $ | 6,198 |
General and administrative |  |  | 1,232 |  |  |  | 2,262 |  |  |  | 4,128 |  |  |  | 6,639 |
Total share-based compensation |  | $ | 1,773 |  |  | $ | 4,055 |  |  | $ | 6,660 |  |  | $ | 12,837 |
The total unrecognized compensation cost related to unvested stock options was $12.1 million, which is expected to be recognized over a weighted average remaining service period of 2.5 years as of September 30, 2025. The total unrecognized compensation cost related to unvested restricted stock units was $2.1 million, which is expected to be recognized over a weighted average remaining service period of 2.6 years as of September 30, 2025. Sale of Common Stock and Pre-funded Warrants In March 2024, the Company completed an underwritten public offering utilizing the Shelf Registration Statement (as defined below), pursuant to which it sold an aggregate of (i) 21,010,000 shares of its common stock at a price of $10.00 per share, and (ii) pre-funded warrants to purchase 3,000,031 shares of its common stock at a price of $9.9999 per pre-funded warrant. The pre-funded warrants can be exercised at any time after issuance for an exercise price of $0.0001 per share, subject to certain ownership limitations. As of June 30, 2025, none of the pre-funded warrants have been exercised. The Company raised $240.1 million in gross proceeds before underwriting discounts and commissions of $14.4 million and other offering expenses of $0.6 million. In accordance with ASC 480-10, Accounting for Certain Financial Instruments with Characteristics of both Liabilities and Equity, and ASC 815-40, Accounting for Derivative Financial Instruments Indexed to, and Potentially Settled in, a Company’s Own Stock, the Company determined that the pre-funded warrants should be equity classified because they are freestanding financial instruments, are immediately exercisable, do not embody an obligation for the Company to repurchase its shares, permit the holders to receive a fixed number of shares of common stock upon exercise, are indexed to the Company’s common stock and meet the equity classification criteria.

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