XML 34 R28.htm IDEA: XBRL DOCUMENT
v3.25.3

Segment Reporting (Tables) | 9 Months Ended
--- | ---
Sep. 30, 2025
Segment Reporting [Abstract] |
Summary of Reconciliation to Net Loss | A reconciliation to the net loss for the three and nine months ended September 30, 2025 and 2024 is included at the bottom of the table below.
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
Segment expenses: |  |  |  |  |  |  |  |  |  |  |  |
Personnel related expenses, excluding share-based compensation(1) |  |  | 8,125 |  |  |  | 10,674 |  |  | $ | 31,739 |  |  | $ | 31,083 |
Facilities expenses |  |  | 5,241 |  |  |  | 4,683 |  |  |  | 14,577 |  |  |  | 14,035 |
Direct external development program expenses |  |  | 4,644 |  |  |  | 5,807 |  |  |  | 14,913 |  |  |  | 16,876 |
Other segment expenses (2) |  |  | 4,406 |  |  |  | 6,228 |  |  |  | 15,420 |  |  |  | 15,576 |
Total segment expenses: |  |  | 22,416 |  |  |  | 27,392 |  |  |  | 76,649 |  |  |  | 77,570 |
Segment loss |  |  | (22,416 | ) |  |  | (27,392 | ) |  |  | (76,649 | ) |  |  | (77,570 | )
Reconciling items: |  |  |  |  |  |  |  |  |  |  |  |
Depreciation and amortization |  |  | (2,306 | ) |  |  | (2,347 | ) |  |  | (6,936 | ) |  |  | (6,864 | )
Share-based compensation |  |  | (1,773 | ) |  |  | (4,055 | ) |  |  | (6,660 | ) |  |  | (12,837 | )
Impairment of right-of-use asset |  |  | (791 | ) |  |  | — |  |  |  | (791 | ) |  |  | — |
Interest income |  |  | 3,852 |  |  |  | 5,453 |  |  |  | 12,198 |  |  |  | 14,423 |
Other income (expense), net |  |  | 1,719 |  |  |  | (3 | ) |  |  | 2,163 |  |  |  | (7 | )
Net loss |  | $ | (21,715 | ) |  | $ | (28,344 | ) |  | $ | (76,675 | ) |  | $ | (82,855 | )
(1) Personnel related expenses include ($0.1) million and $5.0 million of severance and other benefits expense for the three and nine months ended September 30, 2025, respectively. (2) Other segment items include consultants and contractor, lab supplies, and general business expenses.

X
- Definition Tabular disclosure of the reconciliation of profit (loss) from reportable segments to the consolidated income (loss) before income tax expense (benefit) and discontinued operations. Includes, but is not limited to, reconciliation after income tax if income tax is allocated to the reportable segment. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 31 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-31 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
Name: | us-gaap_ReconciliationOfOperatingProfitLossFromSegmentsToConsolidatedTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- References No definition available. + Details
Name: | us-gaap_SegmentReportingAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration