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Stockholders' Equity (Tables)

9 Months Ended

Sep. 30, 2025

Stockholders' Equity Note [Abstract]

Summary of Stock Option Activity

The following table summarizes the option activity under the 2020 Plan and 2015 Plan during the nine months ended September 30, 2025:

		Number of shares				Weighted average exercise price				Weighted average remaining contractual term (in years)				Aggregate Intrinsic Value
Outstanding at December 31, 2024			9,069,194			$	10.55				7.0			$	263
Granted			4,450,219				2.12
Forfeited			(2,570,533	)			5.64
Outstanding at September 30, 2025			10,948,880			$	8.28				6.3			$	668
Exercisable at September 30, 2025			6,151,152			$	12.14				4.1			$	27
Vested and expected to vest at September 30, 2025			10,948,880			$	8.28				6.3			$	668

Summary of Restricted Stock Unit Activity

The following table summarizes the restricted stock unit activity under the 2020 Plan during the nine months ended September 30, 2025:

		Number of shares				Weighted average grant date fair value per share				Weighted average remaining contractual term (in years)
Outstanding at December 31, 2024			1,167,911			$	6.71				1.4
Granted			778,078				2.50
Vested			(327,242	)			6.87
Forfeited			(957,111	)			4.87
Outstanding at September 30, 2025			661,636			$	4.34				1.5

Summary of Share-based Compensation Expense

Share-based compensation expense for the three and nine months ended September 30, 2025 and 2024 was as follows (in thousands):

		Three Months Ended September 30,								Nine Months Ended September 30,
		2025				2024				2025				2024
Research and development		$	541			$	1,793			$	2,532			$	6,198
General and administrative			1,232				2,262				4,128				6,639
Total share-based compensation		$	1,773			$	4,055			$	6,660			$	12,837

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- Definition

Tabular disclosure of cost recognized for award under share-based payment arrangement by plan. Includes, but is not limited to, related tax benefit.

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Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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