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Nature of Activities and Summary of Significant Accounting Policies (Details 2) - shares | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Total number of potentially dilutive shares excluded from the basic and diluted net loss per share calculation (in thousands) | 5,167,000,000 | 6,852,000,000 | 5,234,000,000
Series B preferred (post split basis) |  |  |
Total number of potentially dilutive shares excluded from the basic and diluted net loss per share calculation (in thousands) | 128 | 132 | 132
Common stock options and warrants |  |  |
Total number of potentially dilutive shares excluded from the basic and diluted net loss per share calculation (in thousands) | 3,819 | 5,422 | 3,840
Debt with conversion feature at $30 per share of common stock |  |  |
Total number of potentially dilutive shares excluded from the basic and diluted net loss per share calculation (in thousands) | 1,220 | 1,298 | 1,262

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- Definition Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257 + Details
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