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Note 1 - Nature of Activities and Summary of Significant Accounting Policies - Schedule of Dilutive Securities (Details) - shares
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Total Number of Potentially Dilutive Shares Excluded from the basic and diluted net loss per share calculation (in shares) 6,447 5,338
Series B Convertible Preferred Stock [Member]    
Total Number of Potentially Dilutive Shares Excluded from the basic and diluted net loss per share calculation (in shares) 127 129
Common Stock Options and Warrants [Member]    
Total Number of Potentially Dilutive Shares Excluded from the basic and diluted net loss per share calculation (in shares) 5,064 3,929
Debt with Conversion Feature [Member]    
Total Number of Potentially Dilutive Shares Excluded from the basic and diluted net loss per share calculation (in shares) 1,256 1,280