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Note 1 - Nature of Activities and Summary of Significant Accounting Policies - Schedule of Dilutive Securities (Details) - shares
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Total Number of Potentially Dilutive Shares Excluded from the basic and diluted net loss per share calculation (in shares) 6,417 5,167
Series B Convertible Preferred Stock [Member]    
Total Number of Potentially Dilutive Shares Excluded from the basic and diluted net loss per share calculation (in shares) 127 128
Common Stock Options and Warrants [Member]    
Total Number of Potentially Dilutive Shares Excluded from the basic and diluted net loss per share calculation (in shares) 5,050 3,819
Debt with Conversion Feature [Member]    
Total Number of Potentially Dilutive Shares Excluded from the basic and diluted net loss per share calculation (in shares) 1,240 1,220