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Property and equipment, net
 9 Months Ended
Sep. 30, 2021
Property and equipment, net  
Property and equipment, net

7. Property and equipment, net

Property and equipment, net consisted of the following (in thousands):

​

​

​

​

​

​

​

​

    

September 30, 

​

December 31, 

​

    

2021

    

2020

Manufacturing and laboratory equipment

​

$

13,198

​

$

12,961

Computer hardware and software

​

 

1,637

​

 

1,088

Office furniture and fixtures

​

 

723

​

 

343

Leasehold improvements

​

​

3,012

​

​

2,996

Construction-in-process

​

 

1,454

​

 

—

​

​

 

20,024

​

 

17,388

Less: Accumulated depreciation

​

 

(11,391)

​

 

(10,336)

​

​

$

8,633

​

$

7,052

​

Depreciation and amortization expense related to property and equipment was $0.4 million and $0.3 million for the three months ended September 30, 2021 and 2020, respectively. Depreciation and amortization expense related to property and equipment was $1.1 million and $1.2 million for the nine months ended September 30, 2021 and 2020, respectively. The Company had zero fully depreciated assets disposed of during the three months ended September 30, 2021 and 2020, and less than $0.1 million and zero fully depreciated assets disposed of during the nine months ended September 30, 2021 and 2020, respectively.

As of September 30, 2021 and December 31, 2020, the Company's office furniture and fixtures shown in the above table included assets under a capital lease in the amount of $0.4 million and zero, respectively, and accumulated depreciation of less than $0.1 million and zero as of September 30, 2021 and December 31, 2020, respectively. As of September 30, 2021, future minimum lease payments under the capital lease were $0.6 million, with $0.2 million representing interest. The capital lease obligation is recorded in other long-term liabilities within the consolidated balance sheet.