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Property and equipment, net (Details) - USD ($)
$ in Thousands
Sep. 30, 2021
Dec. 31, 2020
Property, Plant and Equipment [Line Items]    
Property plant and equipment, gross $ 20,024 $ 17,388
Less: Accumulated depreciation (11,391) (10,336)
Property plant and equipment, net 8,633 7,052
Manufacturing and laboratory equipment    
Property, Plant and Equipment [Line Items]    
Property plant and equipment, gross 13,198 12,961
Computer hardware and software    
Property, Plant and Equipment [Line Items]    
Property plant and equipment, gross 1,637 1,088
Office furniture and fixtures    
Property, Plant and Equipment [Line Items]    
Property plant and equipment, gross 723 343
Leasehold improvements    
Property, Plant and Equipment [Line Items]    
Property plant and equipment, gross 3,012 $ 2,996
Construction-in-process    
Property, Plant and Equipment [Line Items]    
Property plant and equipment, gross $ 1,454