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Property and equipment, net
 3 Months Ended
Mar. 31, 2025
Property, Plant and Equipment [Abstract]  
Property and equipment, net Property and equipment, net
Property and equipment, net consisted of the following (in thousands):
March 31,December 31,
20252024
Manufacturing and laboratory equipment$14,833 $14,457 
Computer hardware and software1,847 1,847 
Office furniture and fixtures682 638 
Leasehold improvements9,378 9,178 
Construction-in-process1,072 1,594 
27,812 27,714 
Less: Accumulated depreciation(17,249)(16,521)
$10,563 $11,193 

Depreciation and amortization expense related to property and equipment was $0.7 million for each of the three months ended March 31, 2025 and 2024.