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<SEC-DOCUMENT>0000950123-10-102175.txt : 20101108
<SEC-HEADER>0000950123-10-102175.hdr.sgml : 20101108
<ACCEPTANCE-DATETIME>20101108092341
ACCESSION NUMBER:		0000950123-10-102175
CONFORMED SUBMISSION TYPE:	6-K
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20101108
FILED AS OF DATE:		20101108
DATE AS OF CHANGE:		20101108

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ONCOLYTICS BIOTECH INC
		CENTRAL INDEX KEY:			0001129928
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		6-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-31062
		FILM NUMBER:		101170883

	BUSINESS ADDRESS:	
		STREET 1:		1167 KENSINGTON CRES NW SUITE 210
		STREET 2:		CALGARY ALBERTA CANADA T2N 1X7
		CITY:			ALBERTA CANADA
		STATE:			A0
		ZIP:			00000
		BUSINESS PHONE:		4036707380

	MAIL ADDRESS:	
		STREET 1:		210 - 1167 KENSINGTON CRES NW
		CITY:			CALGARY
		STATE:			A0
		ZIP:			T2N 1X7
</SEC-HEADER>
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<TYPE>6-K
<SEQUENCE>1
<FILENAME>o66326e6vk.htm
<DESCRIPTION>6-K
<TEXT>
<HTML>
<HEAD>
<TITLE>e6vk</TITLE>
</HEAD>
<BODY bgcolor="#FFFFFF">
<!-- PAGEBREAK -->
<DIV style="font-family: 'Times New Roman',Times,serif">


<DIV style="width: 100%; border-bottom: 2pt solid black; font-size: 1pt">&nbsp;</DIV>
<DIV style="width: 100%; border-bottom: 1pt solid black; font-size: 1pt">&nbsp;</DIV>




<DIV align="center" style="font-size: 14pt; margin-top: 12pt"><B>SECURITIES AND EXCHANGE COMMISSION</B>
</DIV>

<DIV align="center" style="font-size: 12pt"><B>Washington, D.C. 20549</B>
</DIV>

<DIV align="center" style="font-size: 18pt; margin-top: 12pt"><B>Form&nbsp;6-K</B>
</DIV>

<DIV align="center" style="font-size: 12pt; margin-top: 12pt"><B>Report of Foreign Private Issuer</B></DIV>


<DIV align="center" style="font-size: 12pt; margin-top: 12pt"><B>Pursuant to Rule&nbsp;13a-16 or 15d-16<BR>
of the Securities Exchange Act of 1934</B>
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 12pt"><B>For the month of November&nbsp;2010</B></DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 12pt"><B>Commission File Number 000-31062</B></DIV>

<DIV align="center" style="font-size: 24pt; margin-top: 12pt"><B>Oncolytics Biotech Inc.</B>
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 0pt"><I>(Translation of registrant&#146;s name into English)</I></DIV>


<DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>Suite&nbsp;210, 1167 Kensington Crescent NW<BR>
Calgary, Alberta, Canada T2N 1X7</B>
</DIV>

<DIV align="Center" style="font-size: 10pt; margin-top: 0pt"><I>(Address of principal executive offices)</I>
</DIV>
<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Indicate by check mark whether the registrant files or will file annual reports under cover Form
20-F or Form 40-F.
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="47%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="47%">&nbsp;</TD>
</TR>
<TR></TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD align="center" valign="top">Form&nbsp;20-F <FONT style="font-family: Wingdings">&#254;</FONT>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">Form&nbsp;40-F <FONT style="font-family: Wingdings">&#111;</FONT></TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by
Regulation&nbsp;S-T Rule&nbsp;101(b)(1): <FONT style="font-family: Wingdings">&#111;</FONT>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><B>Note: </B>Regulation&nbsp;S-T Rule&nbsp;101(b)(1) only permits the submission in paper of a Form 6-K if submitted
solely to provide an attached annual report to security holders.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by
Regulation&nbsp;S-T Rule&nbsp;101(b)(7): <FONT style="font-family: Wingdings">&#111;</FONT>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><B>Note: </B>Regulation&nbsp;S-T Rule&nbsp;101(b)(7) only permits the submission in paper of a Form 6-K if submitted
to furnish a report or other document that the registrant foreign private issuer must furnish and
make public under the laws of the jurisdiction in which the registrant is incorporated, domiciled
or legally organized (the registrant&#146;s &#147;home country&#148;), or under the rules of the home country
exchange on which the registrant&#146;s securities are traded, as long as the report or other document
is not a press release, is not required to be and has not been distributed to the registrant&#146;s
security holders, and, if discussing a material event, has already been the subject of a Form 6-K
submission or other Commission filing on EDGAR.
</DIV>


<DIV style="width: 100%; border-bottom: 1pt solid black; margin-top: 10pt; font-size: 1pt">&nbsp;</DIV>
<DIV style="width: 100%; border-bottom: 2pt solid black; font-size: 1pt">&nbsp;</DIV>




















<P align="center" style="font-size: 10pt"><!-- Folio --><!-- /Folio -->
</DIV>




<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
<DIV style="font-family: 'Times New Roman',Times,serif">

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="5%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="80%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="left"><B>EXHIBIT</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>NUMBER</B></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="left" style="border-bottom: 1px solid #000000"><B>DESCRIPTION</B></TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD align="center" valign="top"><DIV style="margin-left:0px; text-indent:-0px">99.1
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">News Release Dated November&nbsp;8, 2010 &#151; Oncolytics
Biotech<SUP style="FONT-size: 85%; vertical-align: text-top">&#174;</SUP> Inc. Closes Cdn$28.77 Million Bought Deal
Financing</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>SIGNATURES</B>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused
this report to be signed on its behalf by the undersigned, thereunto duly authorized.
</DIV>


<TABLE width="100%" border="0" cellspacing="0" cellpadding="0" style="font-size: 10pt">
<TR>
    <TD width="48%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="35%">&nbsp;</TD>
    <TD width="15%">&nbsp;</TD>
</TR>
<TR>
    <TD valign="top" align="left">&nbsp;</TD>
    <TD colspan="3" align="left"><BR>
<BR>
<B>Oncolytics Biotech Inc.</B><BR>
(Registrant)<BR>
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">Date:  November 8, 2010 &nbsp;</TD>
    <TD valign="top">By:&nbsp;&nbsp;</TD>
    <TD colspan="2" style="border-bottom: 1px solid #000000" align="left">/s/  Doug Ball
&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">Doug Ball&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR><TR>
    <TD align="left">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD colspan="2" align="left">Chief Financial Officer&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>
<TR>
    <TD colspan="5">&nbsp;</TD>
</TR>
</TABLE>


<P align="center" style="font-size: 10pt"><!-- Folio -->2<!-- /Folio -->
</DIV>



</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>o66326exv99w1.htm
<DESCRIPTION>EX-99.1
<TEXT>
<HTML>
<HEAD>
<TITLE>exv99w1</TITLE>
</HEAD>
<BODY bgcolor="#FFFFFF">
<!-- PAGEBREAK -->
<DIV style="font-family: 'Times New Roman',Times,serif">

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="60%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="30%">&nbsp;</TD>
</TR>
<TR></TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD valign="middle" rowspan="3"><DIV style="margin-left:0px; text-indent:-0px"><IMG src="o66326o6632600.gif" alt="(ONCOLYTICS BIOTECH INC LOGO)">
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">210, 1167 Kensington Cr. N.W</TD>
</TR>
<TR valign="bottom">

    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Calgary, Alberta</TD>
</TR>
<TR>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Canada T2N 1X7</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>Oncolytics Biotech<SUP style="FONT-size: 85%; vertical-align: text-top">&#174;</SUP> Inc. Closes Cdn$28.77 Million Bought Deal Financing</B>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><B>CALGARY, AB &#151; November&nbsp;8, 2010 &#151; </B>Oncolytics Biotech Inc. (&#147;Oncolytics&#148; or the &#147;Company&#148;)
(TSX:ONC, NASDAQ:ONCY) today announced that it has closed its previously announced Cdn$25&nbsp;million
financing in which it entered into an agreement with a syndicate of underwriters pursuant to which
they purchased, on a bought deal basis, 5,440,000 units (the &#147;Units&#148;) of the Company at a price of
Cdn$4.60 per Unit for gross proceeds to the Company of approximately Cdn$25&nbsp;million (the
&#147;Offering&#148;). The Offering was conducted through a syndicate of underwriters (the &#147;Underwriters&#148;).
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">In connection with the Offering, the Underwriters have exercised in full an option (the
&#147;Over-Allotment Option&#148;) to purchase an additional 816,000 Units sold under the Offering at a price
of Cdn$4.60 per Unit, on the same terms and conditions as the Offering. With the Over-Allotment
Option exercised in full, the aggregate gross proceeds of the Offering to Oncolytics is
approximately Cdn$28.77&nbsp;million.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Each Unit consists of one common share of Oncolytics and one-half of one common share purchase
warrant (each whole common share purchase warrant, a &#147;Warrant&#148;). Each Warrant entitles the holder
to acquire one common share of Oncolytics at a price of Cdn$6.15 at any time until November&nbsp;8,
2012.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">&#147;Completion of this financing significantly strengthens our balance sheet and gives us the
necessary resources to fully fund our Phase III trial in head and neck cancers, in parallel with
our broader clinical program,&#148; said Dr.&nbsp;Brad Thompson, President and CEO of Oncolytics.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">The Units were offered in Canada by way of a prospectus supplement to a short-form base shelf
prospectus dated June&nbsp;10, 2010 that has been filed in the provinces of British Columbia, Alberta,
Manitoba and Ontario.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Oncolytics intends to use the net proceeds from the Offering to fund its ongoing Phase III
combination REOLYSIN<SUP style="FONT-size: 85%; vertical-align: text-top">&#174;</SUP> and paclitaxel/carboplatin clinical trial for patients with
platinum-failed head and neck cancers, its other clinical activities, manufacturing activities in
support of its clinical trial program, and for general corporate and working capital purposes.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">The securities issued by Oncolytics have not been and will not be registered under the United
States Securities Act of 1933, as amended (the &#147;1933 Act&#148;), or the securities laws of any state of
the United States, and may not be offered or sold in the United States or to, or for the account or
benefit of, U.S. persons (as defined in Regulation&nbsp;S under the 1933 Act) unless registered under
the 1933 Act and applicable securities laws of any state of the
United States or pursuant to an exemption from such registration requirements. This press release shall not constitute an offer to
sell or the solicitation of an offer to buy nor shall there be any sale of the securities in any
jurisdiction in which such offer, solicitation or sale would be unlawful.
</DIV>


<P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: 'Times New Roman',Times,serif">




<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>About Oncolytics Biotech Inc.</B>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Oncolytics is a Calgary-based biotechnology company focused on the development of oncolytic viruses
as potential cancer therapeutics. Oncolytics&#146; clinical program includes a variety of human trials
including a Phase III trial in head and neck cancers using REOLYSIN, its proprietary formulation of
the human reovirus.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><I>This press release contains forward-looking statements, within the meaning of Section&nbsp;21E of
the Securities Exchange Act of 1934, as amended. Forward-looking statements, including the
Company&#146;s expectations related to the application of proceeds and the ability to fully fund the
program as anticipated; the Company&#146;s belief as to the potential of REOLYSIN as a cancer
therapeutic; the Company&#146;s expectations as to the success of its research and development programs
in 2010 and beyond, the Company&#146;s planned operations, the value of the additional patents and
intellectual property; the Company&#146;s expectations related to the applications of the patented
technology; the Company&#146;s expectations as to adequacy of its existing capital resources; the
design, timing, success of planned clinical trial programs; and other statements related to
anticipated developments in the Company&#146;s business and technologies involve known and unknown risks
and uncertainties, which could cause the Company&#146;s actual results to differ materially from those
in the forward-looking statements. Such risks and uncertainties include, among others, the pricing
and completion of the contemplated offering, availability of funds and resources to pursue research
and development projects, the efficacy of REOLYSIN as a cancer treatment, the success and timely
completion of clinical studies and trials, the Company&#146;s ability to successfully commercialize
REOLYSIN, uncertainties related to the research and development of pharmaceuticals, uncertainties
related to the regulatory process and general changes to the economic environment. Investors
should consult the Company&#146;s quarterly and annual filings with the Canadian and U.S. securities
commissions for additional information on risks and uncertainties relating to the forward-looking
statements. Investors are cautioned against placing undue reliance on forward-looking statements.
The Company does not undertake to update these forward-looking statements, except as required by
applicable laws.</I>
</DIV>



<P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
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`
end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----
