    <SEC-DOCUMENT>0000912282-15-000398-index.html : 20151028
    <SEC-HEADER>0000912282-15-000398.hdr.sgml : 20151028
    <ACCEPTANCE-DATETIME>20151028145822
    ACCESSION NUMBER:		0000912282-15-000398
    CONFORMED SUBMISSION TYPE:	6-K
    PUBLIC DOCUMENT COUNT:		10
    CONFORMED PERIOD OF REPORT:	20150925
    FILED AS OF DATE:		20151028
    DATE AS OF CHANGE:		20151028

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ONCOLYTICS BIOTECH INC
    		CENTRAL INDEX KEY:			0001129928
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		6-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	000-31062
    		FILM NUMBER:		151180015

    	BUSINESS ADDRESS:
    		STREET 1:		1167 KENSINGTON CRES NW SUITE 210
    		STREET 2:		CALGARY ALBERTA CANADA T2N 1X7
    		CITY:			ALBERTA CANADA
    		STATE:			A0
    		ZIP:			00000
    		BUSINESS PHONE:		4036707380

    	MAIL ADDRESS:
    		STREET 1:		210 - 1167 KENSINGTON CRES NW
    		CITY:			CALGARY
    		STATE:			A0
    		ZIP:			T2N 1X7
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>6-K
    <SEQUENCE>1
    <FILENAME>oncolytics6k_10282015.htm
    <TEXT>
    Document 1 - file: oncolytics6k_10282015.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>ex99_1.htm
    <DESCRIPTION>UNDERTAKING TO THE EXECUTIVE DIRECTOR DATED 20150925
    <TEXT>
    Document 2 - file: ex99_1.htm

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>undertaking_p1.jpg
    <TEXT>
    Document 3 - file: undertaking_p1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>undertaking_p2.jpg
    <TEXT>
    Document 4 - file: undertaking_p2.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>undertaking_p3.jpg
    <TEXT>
    Document 5 - file: undertaking_p3.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>undertaking_p4.jpg
    <TEXT>
    Document 6 - file: undertaking_p4.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>undertaking_p5.jpg
    <TEXT>
    Document 7 - file: undertaking_p5.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>undertaking_p7.jpg
    <TEXT>
    Document 8 - file: undertaking_p7.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>undertaking_p8.jpg
    <TEXT>
    Document 9 - file: undertaking_p8.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>undertakingp_6.jpg
    <TEXT>
    Document 10 - file: undertakingp_6.jpg

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    </SEC-DOCUMENT>