<SEC-DOCUMENT>0001129928-16-000013-index.html : 20160324
<SEC-HEADER>0001129928-16-000013.hdr.sgml : 20160324
<ACCEPTANCE-DATETIME>20160324165158
ACCESSION NUMBER:		0001129928-16-000013
CONFORMED SUBMISSION TYPE:	20-F
PUBLIC DOCUMENT COUNT:		17
CONFORMED PERIOD OF REPORT:	20151231
FILED AS OF DATE:		20160324
DATE AS OF CHANGE:		20160324

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ONCOLYTICS BIOTECH INC
		CENTRAL INDEX KEY:			0001129928
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		20-F
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-31062
		FILM NUMBER:		161527725

	BUSINESS ADDRESS:	
		STREET 1:		1167 KENSINGTON CRES NW SUITE 210
		STREET 2:		CALGARY ALBERTA CANADA T2N 1X7
		CITY:			ALBERTA CANADA
		STATE:			A0
		ZIP:			00000
		BUSINESS PHONE:		4036707380

	MAIL ADDRESS:	
		STREET 1:		210 - 1167 KENSINGTON CRES NW
		CITY:			CALGARY
		STATE:			A0
		ZIP:			T2N 1X7
</SEC-HEADER>
<DOCUMENT>
<TYPE>20-F
<SEQUENCE>1
<FILENAME>oncyf2015-20f.htm
<DESCRIPTION>2015 20-F
<TEXT>
Document 1 - file: oncyf2015-20f.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.33
<SEQUENCE>2
<FILENAME>ex433thompson.htm
<DESCRIPTION>AMENDMENT - THOMPSON
<TEXT>
Document 2 - file: ex433thompson.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.34
<SEQUENCE>3
<FILENAME>ex434look.htm
<DESCRIPTION>AMENDMENT - LOOK
<TEXT>
Document 3 - file: ex434look.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.35
<SEQUENCE>4
<FILENAME>ex435coffey.htm
<DESCRIPTION>AMENDMENT - COFFEY
<TEXT>
Document 4 - file: ex435coffey.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.36
<SEQUENCE>5
<FILENAME>ex436tuchman.htm
<DESCRIPTION>AMENDMENT - TUCHMAN
<TEXT>
Document 5 - file: ex436tuchman.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.37
<SEQUENCE>6
<FILENAME>ex437tuchman.htm
<DESCRIPTION>AMENDMENT - TUCHMAN
<TEXT>
Document 6 - file: ex437tuchman.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.38
<SEQUENCE>7
<FILENAME>ex438gill.htm
<DESCRIPTION>AMENDMENT - GILL
<TEXT>
Document 7 - file: ex438gill.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-8.0
<SEQUENCE>8
<FILENAME>ex80listofsubsidiaries2015.htm
<DESCRIPTION>SUBSIDIARIES
<TEXT>
Document 8 - file: ex80listofsubsidiaries2015.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-12.1
<SEQUENCE>9
<FILENAME>ex121ceocertification2015.htm
<DESCRIPTION>CEO CERTIFICATION
<TEXT>
Document 9 - file: ex121ceocertification2015.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-12.2
<SEQUENCE>10
<FILENAME>ex122cfocertification2015.htm
<DESCRIPTION>CFO CERTIFICATION
<TEXT>
Document 10 - file: ex122cfocertification2015.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-13.1
<SEQUENCE>11
<FILENAME>ex131ceocertification2015.htm
<DESCRIPTION>CEO CERTIFICATION
<TEXT>
Document 11 - file: ex131ceocertification2015.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-13.2
<SEQUENCE>12
<FILENAME>ex132cfocertification2015.htm
<DESCRIPTION>CFO CERTIFICATION
<TEXT>
Document 12 - file: ex132cfocertification2015.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-15.1
<SEQUENCE>13
<FILENAME>ex151-2015mda.htm
<DESCRIPTION>2015 MD&A
<TEXT>
Document 13 - file: ex151-2015mda.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-15.2
<SEQUENCE>14
<FILENAME>ex152eyconsentletter2015.htm
<DESCRIPTION>EY CONSENT
<TEXT>
Document 14 - file: ex152eyconsentletter2015.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>15
<FILENAME>image1a01.jpg
<TEXT>
Document 15 - file: image1a01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>16
<FILENAME>image3a01.jpg
<TEXT>
Document 16 - file: image3a01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>17
<FILENAME>image4a01.jpg
<TEXT>
Document 17 - file: image4a01.jpg

</DOCUMENT>
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