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CONSOLIDATED STATEMENTS OF LOSS AND COMPREHENSIVE LOSS - CAD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Expenses      
Research and development $ 9,417,888 $ 9,392,623 $ 9,770,007
Operating 7,244,791 6,212,831 5,524,500
Loss before the following (16,662,679) (15,605,454) (15,294,507)
Interest 173,496 130,101 163,902
Loss before income taxes (16,489,183) (15,475,353) (15,130,605)
Income tax expense (548,042) (141,498) (9,374)
Net loss (17,037,225) (15,616,851) (15,139,979)
Other comprehensive income (loss) items that may be reclassified to net loss      
Translation adjustment 233,774 (180,330) (206,918)
Net comprehensive loss $ (16,803,451) $ (15,797,181) $ (15,346,897)
Basic and diluted loss per common share (cad per share) $ (1.06) $ (1.12) $ (1.20)
Weighted average number of shares (basic) 16,016,366 13,936,387 12,618,942
Weighted average number of shares (diluted) 16,016,366 13,936,387 12,618,942