<SEC-DOCUMENT>0001129928-19-000011-index.html : 20190308
<SEC-HEADER>0001129928-19-000011.hdr.sgml : 20190308
<ACCEPTANCE-DATETIME>20190308140105
ACCESSION NUMBER:		0001129928-19-000011
CONFORMED SUBMISSION TYPE:	6-K
PUBLIC DOCUMENT COUNT:		6
CONFORMED PERIOD OF REPORT:	20181231
FILED AS OF DATE:		20190308
DATE AS OF CHANGE:		20190308

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ONCOLYTICS BIOTECH INC
		CENTRAL INDEX KEY:			0001129928
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		6-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38512
		FILM NUMBER:		19668645

	BUSINESS ADDRESS:	
		STREET 1:		1167 KENSINGTON CRES NW SUITE 210
		STREET 2:		CALGARY ALBERTA CANADA T2N 1X7
		CITY:			ALBERTA CANADA
		STATE:			A0
		ZIP:			00000
		BUSINESS PHONE:		4036707380

	MAIL ADDRESS:	
		STREET 1:		210 - 1167 KENSINGTON CRES NW
		CITY:			CALGARY
		STATE:			A0
		ZIP:			T2N 1X7
</SEC-HEADER>
<DOCUMENT>
<TYPE>6-K
<SEQUENCE>1
<FILENAME>q42018form6k.htm
<DESCRIPTION>2018 FOURTH QUARTER 6-K
<TEXT>
Document 1 - file: q42018form6k.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>oncyf2018-fsfor6k.htm
<DESCRIPTION>DECEMBER 31 2018 CONSOLIDATED FINANCIAL STATEMENTS
<TEXT>
Document 2 - file: oncyf2018-fsfor6k.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.2
<SEQUENCE>3
<FILENAME>ex151-2018mdafor6k.htm
<DESCRIPTION>DECEMBER 31 2018 MD&A
<TEXT>
Document 3 - file: ex151-2018mdafor6k.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>eysignaturea09.jpg
<TEXT>
Document 4 - file: eysignaturea09.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>eysignaturea10.jpg
<TEXT>
Document 5 - file: eysignaturea10.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>oncolyticslogotaglinebluea04.jpg
<TEXT>
Document 6 - file: oncolyticslogotaglinebluea04.jpg

</DOCUMENT>
</SEC-DOCUMENT>