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Other Expenses (Tables) | 12 Months Ended
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Dec. 31, 2021
Analysis of income and expense [abstract] |
Other expenses and adjustments |
For the years ended December 31, | 2021 |  | 2020 |  | 2019
Included in research and development expenses: |  |  |  |  |
Employee compensation and benefits | $ | 4,645,264 |  |  | $ | 3,775,263 |  |  | $ | 3,096,231 |
Share-based compensation | 2,086,608 |  |  | 1,043,373 |  |  | 561,420 |
Included in operating expenses |  |  |  |  |
Depreciation - property and equipment | $ | 130,243 |  |  | $ | 88,957 |  |  | $ | 122,982 |
Depreciation - right-of-use assets | 321,822 |  |  | 357,230 |  |  | 362,592 |
Employee compensation and benefits | 2,542,210 |  |  | 2,635,170 |  |  | 2,555,274 |
Share-based compensation | 1,739,293 |  |  | 1,515,601 |  |  | 908,733 |
Transaction cost, warrant derivative | — |  |  | — |  |  | 233,143 |

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