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Other Expenses
 12 Months Ended
Dec. 31, 2021
Analysis of income and expense [abstract]  
Other Expenses Other Expenses
The following details highlight certain components of the research and development and operating expenses classified by nature. The foreign exchange loss as presented separately on the face of the consolidated statement of loss and comprehensive loss is also classified as a research and development expense. Remaining research and development and operating expenses include expenses paid to third parties.
For the years ended December 31,202120202019
Included in research and development expenses:
Employee compensation and benefits$4,645,264 $3,775,263 $3,096,231 
Share-based compensation2,086,608 1,043,373 561,420 
Included in operating expenses
Depreciation - property and equipment$130,243 $88,957 $122,982 
Depreciation - right-of-use assets321,822 357,230 362,592 
Employee compensation and benefits2,542,210 2,635,170 2,555,274 
Share-based compensation1,739,293 1,515,601 908,733 
Transaction cost, warrant derivative— — 233,143