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Other Expenses (Tables)
 12 Months Ended
Dec. 31, 2021
Analysis of income and expense [abstract]  
Other expenses and adjustments
For the years ended December 31,202120202019
Included in research and development expenses:
Employee compensation and benefits$4,645,264 $3,775,263 $3,096,231 
Share-based compensation2,086,608 1,043,373 561,420 
Included in operating expenses
Depreciation - property and equipment$130,243 $88,957 $122,982 
Depreciation - right-of-use assets321,822 357,230 362,592 
Employee compensation and benefits2,542,210 2,635,170 2,555,274 
Share-based compensation1,739,293 1,515,601 908,733 
Transaction cost, warrant derivative— — 233,143