<SEC-DOCUMENT>0001104659-22-072476-index.html : 20220617
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<ACCEPTANCE-DATETIME>20220617173010
ACCESSION NUMBER:		0001104659-22-072476
CONFORMED SUBMISSION TYPE:	SUPPL
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20220617
DATE AS OF CHANGE:		20220617
EFFECTIVENESS DATE:		20220617

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ONCOLYTICS BIOTECH INC
		CENTRAL INDEX KEY:			0001129928
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SUPPL
		SEC ACT:		
		SEC FILE NUMBER:	333-265510
		FILM NUMBER:		221025190

	BUSINESS ADDRESS:	
		STREET 1:		804, 322 - 11 AVENUE SW
		CITY:			CALGARY
		STATE:			A0
		ZIP:			T2R 0C5
		BUSINESS PHONE:		4036707380

	MAIL ADDRESS:	
		STREET 1:		804, 322 - 11 AVENUE SW
		CITY:			CALGARY
		STATE:			A0
		ZIP:			T2R 0C5
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<DOCUMENT>
<TYPE>SUPPL
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<FILENAME>tm2218797d2_suppl.htm
<DESCRIPTION>SUPPL
<TEXT>
Document 1 - file: tm2218797d2_suppl.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>tm2218797d2_supplimg001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: tm2218797d2_supplimg001.jpg

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