Components of Expenses

12 Months Ended

Dec. 31, 2022

Analysis of income and expense [abstract]


	2022		2021		2020
Research and development expenses
Clinical trial expenses	$	4,970	$	3,205	$	3,055
Manufacturing & related process development expenses	2,148		1,547		3,384
Intellectual property expenses	544		618		907
Translational science expenses	264		673		318
Personnel-related expenses	6,023		4,754		4,135
Share-based compensation expense	1,371		2,087		1,043
Other expenses	112		36		103
	$	15,432	$	12,920	$	12,945

General and administrative expenses
Public company-related expenses	$	6,790	$	8,161	$	7,432
Office expenses	3,303		2,963		3,120
Share-based compensation expense	1,007		1,739		1,516
Depreciation - property and equipment	93		130		89
Depreciation - right-of-use assets	299		322		357
	$	11,492	$	13,315	$	12,514

In 2022, our research and development personnel-related expenses included employee compensation and benefits of $5,983 (2021 - $4,645; 2020 - $3,775).

In 2022, our general and administrative office expenses included employee compensation and benefits of $2,870 (2021 - $2,542; 2020 - $2,635).