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CONSOLIDATED STATEMENTS OF LOSS AND COMPREHENSIVE LOSS - CAD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Expenses      
Research and development (note 19) $ 15,432 $ 12,920 $ 12,945
General and administrative (note 19) 11,492 13,315 12,514
Loss before the following (26,924) (26,235) (25,459)
Change in fair value of warrant derivative (notes 9(b), 16) (20) 17 3,492
Foreign exchange gain (loss) 1,665 (136) (659)
Interest income, net 528 99 121
Loss before income taxes (24,751) (26,255) (22,505)
Income tax expense (note 14) (84) (49) 0
Net loss (24,835) (26,304) (22,505)
Other comprehensive income (loss) items that may be reclassified to net loss      
Translation adjustment 274 (12) (64)
Net comprehensive loss $ (24,561) $ (26,316) $ (22,569)
Basic loss per common share (cad per share) $ (0.43) $ (0.49) $ (0.56)
Diluted loss per common share (cad per share) $ (0.43) $ (0.49) $ (0.56)
Weighted average number of shares (basic) (shares) 58,029,745 53,513,225 40,338,789
Weighted average number of shares (diluted) (shares) 58,029,745 53,513,225 40,338,789