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Components of Expenses (Details) - CAD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Research and development expenses      
Share-based compensation expense $ 2,378 $ 3,826 $ 2,559
Research and development expenses 15,432 12,920 12,945
General and administrative expenses      
Depreciation - right-of-use assets 299 322  
General and administrative expenses 11,492 13,315 12,514
Research and development expenses      
Research and development expenses      
Clinical trial expenses 4,970 3,205 3,055
Manufacturing & related process development expenses 2,148 1,547 3,384
Intellectual property expenses 544 618 907
Translational science expenses 264 673 318
Personnel-related expenses 6,023 4,754 4,135
Share-based compensation expense 1,371 2,087 1,043
Other expenses 112 36 103
General and administrative expenses      
Employee compensation and benefits expense 5,983 4,645 3,775
General and administrative expenses      
Research and development expenses      
Share-based compensation expense 1,007 1,739 1,516
General and administrative expenses      
Public company-related expenses 6,790 8,161 7,432
Office expenses 3,303 2,963 3,120
Depreciation - property and equipment 93 130 89
Depreciation - right-of-use assets 299 322 357
Employee compensation and benefits expense $ 2,870 $ 2,542 $ 2,635