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Stockholders' Equity (Tables)

9 Months Ended

Sep. 30, 2021

Stockholders' Equity Note [Abstract]

Schedule of Stock-Based Compensation Expense

Stock-based compensation expense related to Cardiff Oncology equity awards have been recognized in operating results as follows:

			Three Months Ended September 30,												Nine Months Ended September 30,
(in thousands)			2021						2020						2021						2020
Included in research and development expense			$	174					$	104					$	286					$	251
Included in selling, general and administrative expense			766						258						1,958						570
Total stock-based compensation expense			$	940					$	362					$	2,244					$	821

Schedule of Assumptions to Estimate Fair Value of Stock Option Awards

The estimated fair value of stock option awards was determined on the date of grant using the Black-Scholes option valuation model with the following weighted-average assumptions during the following periods indicated:

			Nine Months Ended September 30,
			2021						2020
Risk-free interest rate			0.95		%				0.44		%
Dividend yield			0		%				0		%
Expected volatility of Cardiff Oncology common stock			108		%				105		%
Expected term			6.0 years						5.9 years

Summary of Stock Option Activity and of Changes in Stock Options Outstanding

A summary of stock option activity and changes in stock options outstanding is presented below:

			Total Options						Weighted-Average Exercise Price Per Share						Intrinsic Value
Balance outstanding, December 31, 2020			1,860,507						$	7.43					$	27,963,363
Granted			1,721,314						$	7.48
Canceled / Forfeited			(10,770)						$	2.55
Expired			(4,219)						$	216.00
Balance outstanding, September 30, 2021			3,566,832						$	7.22					$	7,522,769
Exercisable at September 30, 2021			1,281,604						$	8.96					$	5,103,890
Vested and expected to vest at September 30, 2021			3,466,323						$	7.28					$	7,344,075

Schedule of Share-based Compensation, Restricted Stock and Restricted Stock Units Activity

A summary of the RSU activity is presented below:

			Total Restricted Stock Units						Weighted-Average Grant Date Fair Value Per Share						Intrinsic Value
Non-vested RSUs outstanding, December 31, 2020			491						$	147.60					$	8,833
Vested			(491)						$	147.60
Non-vested RSUs outstanding, September 30, 2021			—						$	—					$	—

Summary of Warrant Activity and Changes in Warrants Outstanding

A summary of warrant activity and changes in warrants outstanding, including both liability and equity classifications is presented below:

			Total Warrants						Weighted-Average Exercise Price Per Share						Weighted-Average Remaining Contractual Term
Balance outstanding, December 31, 2020			5,260,992						$	5.19					4.1 years
Exercised			(770,833)						$	1.64
Balance outstanding, September 30, 2021			4,490,159						$	5.80					3.2 years

Schedule of Preferred Stock

A summary of our Company's classes of preferred stock is presented below:

																								Shares outstanding
Class						Par value						Shares designated						Liquidation preference						As of September 30, 2021						As of December 31, 2020
Series A Convertible Preferred Stock						$	0.001					277,100						$	606,000					60,600						60,600
Series B Convertible Preferred Stock						$	0.001					8,860						None						—						—
Series C Convertible Preferred Stock						$	0.001					200,000						None						—						—
Series D Convertible Preferred Stock						$	0.0001					154,670						None						—						—
Series E Convertible Preferred Stock						$	0.001					865,824						None						655,044						655,044

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