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Derivative Financial Instruments - Warrants (Details) $ / shares in Units, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021 USD ($) $ / shares shares	Sep. 30, 2020 USD ($)	Sep. 30, 2021 USD ($) $ / shares shares	Sep. 30, 2020 USD ($)	Dec. 31, 2020 $ / shares
Changes in the Company's derivative financial instruments liability balance
Balance of warrants outstanding at the beginning of the period (in shares) | shares			5,260,992
Balance of warrants outstanding at the end of the period (in shares) | shares	4,490,159		4,490,159
Balance of derivative financial instruments liability at the beginning of the period			$ 285
Change in fair value of derivative financial instruments—warrants during the period recognized as a gain in the condensed statements of operations	$ 12	$ (144)	280	$ (186)
Balance of derivative financial instruments liability at the end of the period	$ 5		$ 5
Warrants to purchase Common Stock
Range of assumptions used to determine the fair value of warrants
Estimated fair value of Cardiff Oncology common stock (in dollars per share) | $ / shares	$ 6.66		$ 6.66		$ 17.99
Warrants to purchase Common Stock | Black Scholes Option Pricing Method
Changes in the Company's derivative financial instruments liability balance
Balance of warrants outstanding at the beginning of the period (in shares) | shares			64,496
Balance of warrants outstanding at the end of the period (in shares) | shares	64,496		64,496
Balance of derivative financial instruments liability at the beginning of the period			$ 285
Change in fair value of derivative financial instruments—warrants during the period recognized as a gain in the condensed statements of operations			(280)
Balance of derivative financial instruments liability at the end of the period	$ 5		$ 5
Expected warrant term | Warrants to purchase Common Stock
Range of assumptions used to determine the fair value of warrants
Expected warrant term	1 year 3 months 18 days		1 year 3 months 18 days		2 years 1 month 6 days
Risk-free interest rate | Warrants to purchase Common Stock
Range of assumptions used to determine the fair value of warrants
Measurement input	0.0015		0.0015		0.0013
Expected volatility of Cardiff Oncology common stock | Warrants to purchase Common Stock
Range of assumptions used to determine the fair value of warrants
Measurement input	1		1		1.16
Dividend yield | Warrants to purchase Common Stock
Range of assumptions used to determine the fair value of warrants
Measurement input	0		0		0

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Number of warrants or rights outstanding.

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Fair value, after the effects of master netting arrangements, of a financial liability or contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset, expected to be settled after one year or the normal operating cycle, if longer. Includes assets not subject to a master netting arrangement and not elected to be offset.

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The net change in the difference between the fair value and the carrying value, or in the comparative fair values, of derivative instruments, including options, swaps, futures, and forward contracts, held at each balance sheet date, that was included in earnings for the period.

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Value of input used to measure outstanding warrant and right embodying unconditional obligation requiring redemption by transferring asset at specified or determinable date or upon event certain to occur.

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Period between issuance and expiration of outstanding warrant and right embodying unconditional obligation requiring redemption by transferring asset at specified or determinable date or upon event certain to occur, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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