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Stockholders' Equity - Stock Option Activity (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2021
Sep. 30, 2020
Dec. 31, 2020
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures        
Authorized shares under the plan (in shares) 3,150,000 3,150,000    
Options to purchase Common Stock        
Weighted-average assumptions        
Risk-free interest rate   0.95% 0.44%  
Dividend yield (as a percent)   0.00% 0.00%  
Expected volatility (as a percent)   108.00% 105.00%  
Expected term   6 years 5 years 10 months 24 days  
Number of Options        
Balance outstanding at the beginning of the period (in shares)   1,860,507    
Granted (in shares)   1,721,314    
Cancelled / Forfeited (in shares)   (10,770)    
Expired (in shares)   (4,219)    
Balance outstanding at the end of the period (in shares) 3,566,832 3,566,832    
Exercisable at the end of the period (in shares) 1,281,604 1,281,604    
Vested and expected to vest at June 30, 2021 (in shares) 3,466,323 3,466,323    
Weighted Average Exercise Price Per Share        
Balance outstanding at the beginning of the period (in USD per share)   $ 7.43    
Granted (in USD per share)   7.48    
Canceled / Forfeited (in USD per share)   2.55    
Expired (in USD per share)   216.00    
Balance outstanding at the end of the period (in USD per share) $ 7.22 7.22    
Exercisable at the end of the period (in USD per share) 8.96 8.96    
Vested and expected to vest at June 30, 2021 (in USD per share) $ 7.28 $ 7.28    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures        
Options outstanding, intrinsic value $ 7,522,769 $ 7,522,769   $ 27,963,363
Exercisable at the end of the period, intrinsic value 5,103,890 5,103,890    
Vested and expected to vest at March 31, 2021, intrinsic value 7,344,075 $ 7,344,075    
Accelerated compensation expense $ 600,000      
Inducement Grant Stock Options        
Number of Options        
Granted (in shares) 590,000      
Equity Incentive Plan 2021        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures        
Number of remaining shares available for issuance (in shares) 2,289,902 2,289,902