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Basis of Presentation and Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2021
Accounting Policies [Abstract] |
Useful Life of Property and Equipment | The estimated useful lives of the major classes of property and equipment are as follows:
| Estimated Useful Lives
Furniture and office equipment | 3 to 5 years
Leasehold improvements | 5 to 6 years
Laboratory equipment | 5 years
Property and equipment consisted of the following:
| As of December 31,
(in thousands) | 2021 |  | 2020
Furniture and office equipment | $ | 955 |  |  | $ | 798 |
Leasehold improvements | 1,962 |  |  | 1,962 |
Laboratory equipment | 906 |  |  | 868 |
| 3,823 |  |  | 3,628 |
Less—accumulated depreciation | (3,441) |  |  | (3,004) |
Property and equipment, net | $ | 382 |  |  | $ | 624 |
Schedule of Antidilutive Securities Excluded from the Calculation of Basic and Diluted Loss Per Share | Shares used in calculating diluted net loss per common share exclude as anti-dilutive the following share equivalents:
| December 31,
| 2021 |  | 2020 |  |
Options to purchase Common Stock | 3,771,984 |  |  | 1,860,507 |  |  |
Warrants to purchase Common Stock | 4,490,159 |  |  | 5,260,992 |  |  |
Restricted Stock Units | — |  |  | 491 |  |  |
Series A Convertible Preferred Stock | 877 |  |  | 877 |  |  |
Series E Convertible Preferred Stock | 2,684,607 |  |  | 2,684,607 |  |  |
| 10,947,627 |  |  | 9,807,474 |  |  |

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- Definition Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(13)) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257 + Details
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