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Supplementary Balance Sheet Information (Tables)

12 Months Ended

Dec. 31, 2021

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Components of Short-term investments

Short-term investments available-for-sale securities consist of the following:

			As of December 31, 2021
(in thousands)			Amortized Cost						Gross Unrealized Gains						Gross Unrealized Losses						Fair Market Value
Maturity less than 1 year:
Certificate of deposit			$	1,260					$	—					$	—					$	1,260
Corporate debt securities			58,822						2						(38)						58,786
Commercial paper			14,453						4						(3)						14,454
Non U.S. government			728						—						—						728
U.S. treasury securities			20,380						—						(24)						20,356
Total maturity less than 1 year			95,643						6						(65)						95,584
Maturity 1 to 2 years:
Corporate debt securities			29,676						1						(73)						29,604
U.S. treasury securities			3,701						—						(11)						3,690
Total maturity 1 to 2 years			33,377						1						(84)						33,294
Total short-term investments			$	129,020					$	7					$	(149)					$	128,878

Components of Property and Equipment

The estimated useful lives of the major classes of property and equipment are as follows:

			Estimated Useful Lives
Furniture and office equipment			3 to 5 years
Leasehold improvements			5 to 6 years
Laboratory equipment			5 years

Property and equipment consisted of the following:

			As of December 31,
(in thousands)			2021						2020
Furniture and office equipment			$	955					$	798
Leasehold improvements			1,962						1,962
Laboratory equipment			906						868
			3,823						3,628
Less—accumulated depreciation			(3,441)						(3,004)
Property and equipment, net			$	382					$	624

Components of Accrued Liabilities

Accrued liabilities consisted of the following:

			As of December 31,
(in thousands)			2021						2020
Accrued compensation			$	1,435					$	1,523
Preferred stock dividend			414						390
Clinical trials			1,639						1,557
Research agreements and services			726						67
Director fees			141						93
Professional fees and outside services			63						38
Patent, license and other fees			43						117
Other accrued liabilities			66						66
Total accrued liabilities			$	4,527					$	3,851

X

- Definition

Tabular disclosure of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 320
-URI http://asc.fasb.org/topic&trid=2196928

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- Definition

Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(13))
-URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

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-Topic 360
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