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Supplementary Balance Sheet Information - Property and Equipment (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Property, Plant and Equipment [Line Items]    
Depreciation and amortization $ 500 $ 500
Property and equipment 3,823 3,628
Less—accumulated depreciation (3,441) (3,004)
Property and equipment, net 382 624
Furniture and office equipment    
Property, Plant and Equipment [Line Items]    
Property and equipment 955 798
Leasehold improvements    
Property, Plant and Equipment [Line Items]    
Property and equipment 1,962 1,962
Laboratory equipment    
Property, Plant and Equipment [Line Items]    
Property and equipment $ 906 $ 868