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Stockholders' Equity - Stock-based Compensation Expense (Details) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2022 | Mar. 31, 2021
Stock-based compensation expense |  |
Total stock based compensation expense | $ 1,152 | $ 268
Options vested, fair value | 1 | 24
Research and Development Expense |  |
Stock-based compensation expense |  |
Total stock based compensation expense | 335 | 40
Selling, general and administrative expense |  |
Stock-based compensation expense |  |
Total stock based compensation expense | 817 | $ 228
Options to purchase Common Stock |  |
Stock-based compensation expense |  |
Unrecognized compensation cost | $ 13,300 |
Weighted-average remaining vesting period for recognition | 3 years 2 months 12 days |
Options outstanding, weighted average contractual life | 8 years 3 months 18 days |

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