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Leases
 3 Months Ended
Mar. 31, 2022
Leases [Abstract]  
Leases Leases
 As a lessee, the Company’s current leases include its master facility lease and immaterial equipment leases, all of which are considered operating leases.

Master Facility Lease

The Company currently leases 12,300 square feet of office and lab space in San Diego that expires on February 28, 2027. The lease currently requires monthly payments of approximately $60,000 per month with 3% annual escalation.

Facility Subleases

As a result of corporate restructurings in previous years, the Company vacated a portion of its facility and subleased the space to third parties under three separate sublease agreements, which all expired on December 31, 2021. Prior to the expiration of the sublease agreements, the Company as a sublessor was leasing approximately 16,600 square feet of space to third parties.

The components of lease expense were as follows:
Three Months Ended March 31,
(in thousands)20222021
Operating lease cost$191 $95 
Operating sublease income— (101)
Net operating lease cost$191 $(6)

Supplemental balance sheet information related to leases was as follows:
(in thousands)As of March 31,
2022		As of December 31,
2021
Operating lease ROU assets$2,660 $2,796 
Current operating lease liabilities$665 $551 
Non-current operating lease liabilities2,438 2,568 
Total operating lease liabilities$3,103 $3,119 
Weighted-average remaining lease term–operating leases4.9 years5.2 years
Weighted-average discount rate–operating leases7.0 %7.0 %
Supplemental cash flow and other information related to leases was as follows:
Three Months Ended March 31,
(in thousands)20222021
Cash paid for amounts included in the measurement of lease liabilities:
Operating cash flows from operating leases$70 $240 

Total remaining annual commitments under non-cancelable lease agreements for each of the years ended December 31 are as follows:
(in thousands)
Year Ending December 31, Operating Leases
2022 (excluding the three months ended March 31, 2022)
$480 
2023737 
2024754 
2025775 
2026796 
Thereafter137 
Total future minimum lease payments3,679 
Less imputed interest(576)
Total$3,103 
Leases Leases
 As a lessee, the Company’s current leases include its master facility lease and immaterial equipment leases, all of which are considered operating leases.

Master Facility Lease

The Company currently leases 12,300 square feet of office and lab space in San Diego that expires on February 28, 2027. The lease currently requires monthly payments of approximately $60,000 per month with 3% annual escalation.

Facility Subleases

As a result of corporate restructurings in previous years, the Company vacated a portion of its facility and subleased the space to third parties under three separate sublease agreements, which all expired on December 31, 2021. Prior to the expiration of the sublease agreements, the Company as a sublessor was leasing approximately 16,600 square feet of space to third parties.

The components of lease expense were as follows:
Three Months Ended March 31,
(in thousands)20222021
Operating lease cost$191 $95 
Operating sublease income— (101)
Net operating lease cost$191 $(6)

Supplemental balance sheet information related to leases was as follows:
(in thousands)As of March 31,
2022		As of December 31,
2021
Operating lease ROU assets$2,660 $2,796 
Current operating lease liabilities$665 $551 
Non-current operating lease liabilities2,438 2,568 
Total operating lease liabilities$3,103 $3,119 
Weighted-average remaining lease term–operating leases4.9 years5.2 years
Weighted-average discount rate–operating leases7.0 %7.0 %
Supplemental cash flow and other information related to leases was as follows:
Three Months Ended March 31,
(in thousands)20222021
Cash paid for amounts included in the measurement of lease liabilities:
Operating cash flows from operating leases$70 $240 

Total remaining annual commitments under non-cancelable lease agreements for each of the years ended December 31 are as follows:
(in thousands)
Year Ending December 31, Operating Leases
2022 (excluding the three months ended March 31, 2022)
$480 
2023737 
2024754 
2025775 
2026796 
Thereafter137 
Total future minimum lease payments3,679 
Less imputed interest(576)
Total$3,103