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Supplementary Balance Sheet Information (Tables)

3 Months Ended

Mar. 31, 2022

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Schedule of Investments Available-for-sale

Investments available for sale consist of the following:

			As of March 31, 2022
(in thousands)			Amortized Cost						Gross Unrealized Gains						Gross Unrealized Losses						Fair Market Value
Maturity less than 1 year:
Certificate of deposit			$	9,250					$	4					$	(15)					$	9,239
Corporate debt securities			55,056						1						(293)						54,764
Commercial paper			10,539						—						(71)						10,468
U.S. treasury securities			20,061						—						(122)						19,939
Total maturity less than 1 year			94,906						5						(501)						94,410
Maturity 1 to 2 years:
Corporate debt securities			15,152						—						(252)						14,900
Total maturity 1 to 2 years			15,152						—						(252)						14,900
Total short-term investments			$	110,058					$	5					$	(753)					$	109,310

			As of December 31, 2021
(in thousands)			Amortized Cost						Gross Unrealized Gains						Gross Unrealized Losses						Fair Market Value
Maturity less than 1 year:
Certificate of deposit			$	1,260					$	—					$	—					$	1,260
Corporate debt securities			58,822						2						(38)						58,786
Commercial paper			14,453						4						(3)						14,454
Non U.S. government			728						—						—						728
U.S. treasury securities			20,380						—						(24)						20,356
Total maturity less than 1 year			95,643						6						(65)						95,584
Maturity 1 to 2 years:
Corporate debt securities			29,676						1						(73)						29,604
U.S. treasury securities			3,701						—						(11)						3,690
Total maturity 1 to 2 years			33,377						1						(84)						33,294
Total short-term investments			$	129,020					$	7					$	(149)					$	128,878

Schedule of Components of Property and Equipment

Property and equipment consist of the following:

(in thousands)			As of March 31, 2022						As of December 31, 2021
Furniture and office equipment			$	1,064					$	955
Leasehold improvements			2,046						1,962
Laboratory equipment			912						906
			4,022						3,823
Less—accumulated depreciation and amortization			(3,472)						(3,441)
Property and equipment, net			$	550					$	382

Schedule of Accrued Liabilities

Accrued liabilities consisted of the following:

(in thousands)			As of March 31, 2022						As of December 31, 2021
Accrued compensation			$	878					$	1,435
Preferred stock dividend			420						414
Clinical trials			2,110						1,639
Research agreements and services			992						726
Director fees			141						141
Professional fees and outside services			53						63
Patent, license and other fees			75						43
Other accrued liabilities			69						66
Total accrued liabilities			$	4,738					$	4,527

X

- Definition

Tabular disclosure of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 320
-URI http://asc.fasb.org/topic&trid=2196928

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- Definition

Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(13))
-URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229

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