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Stockholders' Equity (Tables)

3 Months Ended

Mar. 31, 2022

Stockholders' Equity Note [Abstract]

Schedule of Stock-Based Compensation Expense

Stock-based compensation expense related to Cardiff Oncology equity awards have been recognized in operating results as follows:

									Three Months Ended March 31,
(in thousands)															2022						2021
Included in research and development expense															$	335					$	40
Included in selling, general and administrative expense															817						228
Total stock-based compensation expense															$	1,152					$	268

Schedule of Assumptions to Estimate Fair Value of Stock Option Awards

The estimated fair value of stock option awards was determined on the date of grant using the Black-Scholes option valuation model with the following weighted-average assumptions during the following periods indicated:

			Three Months Ended March 31,
			2022
Risk-free interest rate			1.84		%
Dividend yield			0		%
Expected volatility of Cardiff Oncology common stock			106		%
Expected term			6.0 years

Summary of Stock Option Activity and of Changes in Stock Options Outstanding

A summary of stock option activity and changes in stock options outstanding is presented below:

			Total Options						Weighted-Average Exercise Price Per Share						Intrinsic Value
Balance outstanding, December 31, 2021			3,771,984						$	7.13					$	6,405,258
Granted			1,697,536						$	3.19
Canceled / Forfeited			(1,109)						$	31.25
Expired			(800)						$	165.84
Balance outstanding, March 31, 2022			5,467,611						$	5.88					$	65,189
Exercisable at March 31, 2022			1,281,362						$	8.83					$	25,108
Vested and expected to vest at March 31, 2022			5,331,850						$	5.91					$	61,800

Summary of Warrant Activity and Changes in Warrants Outstanding

A summary of warrant activity and changes in warrants outstanding, including both liability and equity classifications is presented below:

			Total Warrants						Weighted-Average Exercise Price Per Share						Weighted-Average Remaining Contractual Term
Balance outstanding, December 31, 2021			4,490,159						$	5.80					3.0 years
Balance outstanding, March 31, 2022			4,490,159						$	5.80					2.7 years

Schedule of Preferred Stock

A summary of our Company's classes of preferred stock is presented below:

																								Shares outstanding
Class						Par value						Shares designated						Liquidation preference						As of March 31, 2022						As of December 31, 2021
Series A Convertible Preferred Stock						$	0.001					277,100						$	606,000					60,600						60,600
Series B Convertible Preferred Stock						$	0.001					8,860						None						—						—
Series C Convertible Preferred Stock						$	0.001					200,000						None						—						—
Series D Convertible Preferred Stock						$	0.0001					154,670						None						—						—
Series E Convertible Preferred Stock						$	0.001					865,824						None						327,509						655,044

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