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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Operating activities    
Net loss $ (21,436) $ (11,936)
Adjustments to reconcile net loss to net cash used in operating activities:    
Loss on disposal of assets 0 1
Depreciation 69 228
Stock-based compensation expense 2,207 1,304
Amortization of premiums on short-term investments 557 698
Change in fair value of derivative financial instruments—warrants 0 (268)
Release of clinical trial funding commitment 139 926
Changes in operating assets and liabilities:    
Other assets 54 141
Accounts receivable and unbilled receivable (16) 12
Prepaid expenses and other assets 18 68
Operating lease right-of-use assets 272 165
Accounts payable and accrued expenses 1,367 (1,121)
Operating lease liabilities (143) (461)
Other liabilities (32) 58
Net cash used in operating activities (16,944) (10,185)
Investing activities:    
Capital expenditures (483) 0
Insurance proceeds from casualty loss 71 0
Maturities of short-term investments 48,801 5,510
Purchases of short-term investments (57,309) (141,948)
Sales of short-term investments 34,886 5,735
Net cash provided by (used in) investing activities 25,966 (130,703)
Financing activities:    
Proceeds from sales of common stock, net of expenses of $0 and $776, respectively 0 19,225
Proceeds from exercise of warrants 0 1,263
Net cash provided by financing activities 0 20,488
Net change in cash and cash equivalents 9,022 (120,400)
Cash and cash equivalents—Beginning of period 11,943 130,981
Cash and cash equivalents—End of period 20,965 10,581
Supplementary disclosure of cash flow activity:    
Cash paid for taxes 1 1
Supplemental disclosure of non-cash investing and financing activities:    
Acquisition of property and equipment included in accounts payable and accrued expenses 456 27
Acquisition of property and equipment included in insurance proceeds receivable 43 0
Preferred stock dividend payable on Series A Convertible Preferred Stock $ 12 $ 12