<SEC-DOCUMENT>0001628280-22-008431-index.html : 20220405
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<ACCEPTANCE-DATETIME>20220405171935
ACCESSION NUMBER:		0001628280-22-008431
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		11
FILED AS OF DATE:		20220405
DATE AS OF CHANGE:		20220405

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Cardiff Oncology, Inc.
		CENTRAL INDEX KEY:			0001213037
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				272004382
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-264148
		FILM NUMBER:		22808175

	BUSINESS ADDRESS:	
		STREET 1:		11055 FLINTKOTE AVENUE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		858-952-7570

	MAIL ADDRESS:	
		STREET 1:		11055 FLINTKOTE AVENUE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Trovagene, Inc.
		DATE OF NAME CHANGE:	20130304

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TrovaGene Inc.
		DATE OF NAME CHANGE:	20110830

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	XENOMICS INC
		DATE OF NAME CHANGE:	20040719
</SEC-HEADER>
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<TYPE>S-3
<SEQUENCE>1
<FILENAME>crdfs-3040522.htm
<DESCRIPTION>S-3
<TEXT>
Document 1 - file: crdfs-3040522.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.3
<SEQUENCE>2
<FILENAME>a43ex040522.htm
<DESCRIPTION>EX-4.3
<TEXT>
Document 2 - file: a43ex040522.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.4
<SEQUENCE>3
<FILENAME>a44ex040522.htm
<DESCRIPTION>EX-4.4
<TEXT>
Document 3 - file: a44ex040522.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>4
<FILENAME>a51ex040522.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 4 - file: a51ex040522.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>5
<FILENAME>a231ex040522.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 5 - file: a231ex040522.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>6
<FILENAME>ex-filingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 6 - file: ex-filingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>cardiff_logoxrgbxtma.jpg
<TEXT>
Document 7 - file: cardiff_logoxrgbxtma.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>image_02.jpg
<TEXT>
Document 8 - file: image_02.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>image_2.jpg
<TEXT>
Document 9 - file: image_2.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>image_210.jpg
<TEXT>
Document 10 - file: image_210.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>image_29.jpg
<TEXT>
Document 11 - file: image_29.jpg

</DOCUMENT>
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