    <SEC-DOCUMENT>0001628280-22-009282-index.html : 20220415
    <SEC-HEADER>0001628280-22-009282.hdr.sgml : 20220415
    <ACCEPTANCE-DATETIME>20220415130238
    ACCESSION NUMBER:		0001628280-22-009282
    CONFORMED SUBMISSION TYPE:	DEFA14A
    PUBLIC DOCUMENT COUNT:		4
    FILED AS OF DATE:		20220415
    DATE AS OF CHANGE:		20220415

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Cardiff Oncology, Inc.
    		CENTRAL INDEX KEY:			0001213037
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		IRS NUMBER:				272004382
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEFA14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-35558
    		FILM NUMBER:		22829525

    	BUSINESS ADDRESS:
    		STREET 1:		11055 FLINTKOTE AVENUE
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    		BUSINESS PHONE:		858-952-7570

    	MAIL ADDRESS:
    		STREET 1:		11055 FLINTKOTE AVENUE
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Trovagene, Inc.
    		DATE OF NAME CHANGE:	20130304

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	TrovaGene Inc.
    		DATE OF NAME CHANGE:	20110830

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	XENOMICS INC
    		DATE OF NAME CHANGE:	20040719
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEFA14A
    <SEQUENCE>1
    <FILENAME>a2022defa14a.htm
    <DESCRIPTION>DEFA14A
    <TEXT>
    Document 1 - file: a2022defa14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>image_0a.jpg
    <TEXT>
    Document 2 - file: image_0a.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>img1a.jpg
    <TEXT>
    Document 3 - file: img1a.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>img2a.jpg
    <TEXT>
    Document 4 - file: img2a.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>