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v3.22.4

Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021
Operating activities |  |  |
Net loss |  | $ (38,704) | $ (28,291)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Loss on disposal of assets |  | 1 | 1
Depreciation |  | 236 | 451
Stock-based compensation expense |  | 4,256 | 3,234
Amortization of premiums on short-term investments |  | 632 | 1,607
Change in fair value of derivative financial instruments—warrants |  | 0 | (285)
Release of clinical trial funding commitment |  | 139 | 2,032
Changes in operating assets and liabilities: |  |  |
Other assets |  | (1,148) | 166
Accounts receivable and unbilled receivable |  | (236) | (215)
Prepaid expenses and other current assets |  | (443) | (2,099)
Operating lease right-of-use assets |  | 545 | 607
Accounts payable and accrued expenses |  | 1,348 | 719
Operating lease liabilities |  | (404) | (811)
Other liabilities |  | (42) | (156)
Net cash used in operating activities |  | (33,820) | (23,040)
Investing activities |  |  |
Capital expenditures |  | (1,006) | (205)
Insurance proceeds from casualty loss |  | 114 | 0
Maturities of short-term investments |  | 76,445 | 28,391
Purchases of short-term investments |  | (91,233) | (174,385)
Sales of short-term investments |  | 53,829 | 14,751
Net cash provided by (used in) investing activities |  | 38,149 | (131,448)
Financing activities |  |  |
Proceeds from sale of common stock, preferred stock and warrants, net of expenses of $0 and $813 respectively |  | 0 | 34,187
Proceeds from exercise of warrants |  | 0 | 1,263
Proceeds from exercise of options |  | 75 | 0
Net cash provided by financing activities |  | 75 | 35,450
Net change in cash and cash equivalents |  | 4,404 | (119,038)
Cash and cash equivalents—Beginning of period |  | 11,943 | 130,981
Cash and cash equivalents—End of period |  | 16,347 | 11,943
Supplementary disclosure of cash flow activity: |  |  |
Cash paid for taxes |  | 2 | 1
Acquisition of property and equipment included in accounts payable and accrued liabilities |  | 232 | 6
Supplemental disclosure of non-cash investing and financing activities: |  |  |
Accretion of Series A Convertible Preferred Stock dividend |  | 0 | 24
Cumulative preferred stock dividend adjustment | [1] | $ (414) | $ 0
[1] | See Note 2 to the financial statements.

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