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Supplementary Balance Sheet Information (Tables)
 12 Months Ended
Dec. 31, 2022
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Components of Short-term investments
Short-term investments available-for-sale securities consist of the following:

As of December 31, 2022
(in thousands)Amortized CostGross Unrealized GainsGross Unrealized LossesFair Market Value
Maturity less than 1 year:
Certificate of deposit$16,101 $3 $(81)$16,023 
Corporate debt securities44,806 8 (275)44,539 
Commercial paper13,203 4 (20)13,187 
U.S. government agencies2,284 4 — 2,288 
U.S. treasury securities7,905 — (18)7,887 
Total maturity less than 1 year84,299 19 (394)83,924 
Maturity 1 to 2 years:
Corporate debt securities5,016 1 (21)4,996 
Total maturity 1 to 2 years5,016 1 (21)4,996 
Total short-term investments$89,315 $20 $(415)$88,920 




As of December 31, 2021
(in thousands)Amortized CostGross Unrealized GainsGross Unrealized LossesFair Market Value
Maturity less than 1 year:
Certificate of deposit$1,260 $— $— $1,260 
Corporate debt securities58,822 2 (38)58,786 
Commercial paper14,453 4 (3)14,454 
Non U.S. government728 — — 728 
U.S. treasury securities20,380 — (24)20,356 
Total maturity less than 1 year95,643 6 (65)95,584 
Maturity 1 to 2 years:
Corporate debt securities29,676 1 (73)29,604 
U.S. treasury securities3,701 — (11)3,690 
Total maturity 1 to 2 years33,377 1 (84)33,294 
Total short-term investments$129,020 $7 $(149)$128,878 
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value Investments available for sale that have been in a continuous unrealized loss position for greater than one-year consist of the following:
As of December 31, 2022
(in thousands)Fair Market ValueGross Unrealized Loss
Corporate debt securities$17,084 $(161)
U.S. treasury securities3,666 (14)
Total short-term investments$20,750 $(175)
Components of Property and Equipment The estimated useful lives of the major classes of property and equipment are as follows:
Estimated Useful Lives
Furniture and office equipment
3 to 5 years
Leasehold improvements
4 to 6 years
Laboratory equipment5 years
Property and equipment consisted of the following:
 As of December 31,
(in thousands)20222021
Furniture and office equipment$1,066 $955 
Leasehold improvements2,560 1,962 
Laboratory equipment1,056 906 
 4,682 3,823 
Less—accumulated depreciation(3,413)(3,441)
Property and equipment, net$1,269 $382 
Components of Accrued Liabilities
Accrued liabilities consisted of the following:

 As of December 31,
(in thousands)20222021
Accrued compensation$1,849 $1,435 
Preferred stock dividend(1)
— 414 
Clinical trials2,333 1,639 
Research agreements and services509 726 
Director fees125 141 
Patent, license and other fees24 43 
Other accrued liabilities337 129 
Total accrued liabilities$5,177 $4,527 
(1)See Note 2 to the financial statements.