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Basis of Presentation and Summary of Significant Accounting Policies - Anti-dilutive Share Equivalents (Details) - shares
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Net Loss Per Share    
Antidilutive securities excluded from computation of earnings per share (in shares) 9,431,303 10,947,627
Options to purchase Common Stock    
Net Loss Per Share    
Antidilutive securities excluded from computation of earnings per share (in shares) 5,069,458 3,771,984
Warrants to purchase Common Stock    
Net Loss Per Share    
Antidilutive securities excluded from computation of earnings per share (in shares) 4,360,968 4,490,159
Series A Convertible Preferred Stock    
Net Loss Per Share    
Antidilutive securities excluded from computation of earnings per share (in shares) 877 877
Series E Convertible Preferred Stock    
Net Loss Per Share    
Antidilutive securities excluded from computation of earnings per share (in shares) 0 2,684,607