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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Operating activities    
Net loss $ (22,373) $ (21,436)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 188 69
Stock-based compensation expense 2,645 2,207
Amortization of premiums (discounts) on short-term investments (405) 557
Release of clinical trial funding commitment 0 139
Changes in operating assets and liabilities:    
Other assets (3) 54
Accounts receivable and unbilled receivable 610 (16)
Prepaid expenses and other assets 2,260 18
Operating lease right-of-use assets 273 272
Accounts payable and accrued expenses 1,293 1,367
Operating lease liabilities (279) (143)
Other liabilities 0 (32)
Net cash used in operating activities (15,791) (16,944)
Investing activities:    
Capital expenditures (259) (483)
Insurance proceeds from casualty loss   71
Maturities of short-term investments 68,265 48,801
Purchases of short-term investments (50,868) (57,309)
Sales of short-term investments 1,675 34,886
Net cash provided by investing activities 18,813 25,966
Financing activities:    
Net cash provided by financing activities 0 0
Net change in cash and cash equivalents 3,022 9,022
Cash and cash equivalents—Beginning of period 16,347 11,943
Cash and cash equivalents—End of period 19,369 20,965
Supplementary disclosure of cash flow activity:    
Cash paid for taxes 1 1
Supplemental disclosure of non-cash investing and financing activities:    
Acquisition of property and equipment included in accounts payable and accrued expenses $ 16 456
Acquisition of property and equipment included in insurance proceeds receivable   $ 43