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Document and Entity Information - USD ($)
 12 Months Ended
Dec. 31, 2023
Feb. 22, 2024
Jun. 30, 2023
Document and Entity Information      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2023    
Current Fiscal Year End Date --12-31    
Document Transition Report false    
Entity File Number 001-35558    
Entity Registrant Name CARDIFF ONCOLOGY, INC.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 27-2004382    
Entity Address, State or Province CA    
Entity Address, City or Town San Diego    
Entity Address, Address Line One 11055 Flintkote Avenue    
Entity Address, Postal Zip Code 92121    
City Area Code 858    
Local Phone Number 952-7570    
Title of 12(b) Security Common Stock, $0.0001 par value    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Emerging Growth Company false    
Entity Small Business true    
ICFR Auditor Attestation Flag false    
Document Financial Statement Error Correction [Flag] false    
Entity Shell Company false    
Entity Public Float     $ 64,335,342
Entity Common Stock, Shares Outstanding (shares)   44,677,169  
Documents Incorporated by Reference
DOCUMENTS INCORPORATED BY REFERENCE
Specified portions of the registrant's proxy statement, which will be filed with the Securities and Exchange Commission pursuant to Regulation 14 A in connection with the registrant's 2023 Annual Meeting of Stockholders (the "Proxy Statement"), are incorporated by reference into Part III of this Annual Report on Form 10-K. Except with respect to information specifically incorporated by reference in this Annual Report, the Proxy Statement is not deemed to be filed as part hereof.
    
Entity Central Index Key 0001213037    
Document Fiscal Year Focus 2023    
Document Fiscal Period Focus FY    
Amendment Flag false