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Basis of Presentation and Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2024
Accounting Policies [Abstract] |
Summary of Segment Reconciliation |
|  | Year Ended December 31, |
(in thousands) |  | 2024 |  |  | 2023 |
Research and development: |  |  |  |  |  |
Salaries and staff costs |  | $ | 6,903 |  |  | $ | 5,930 |
Stock-based compensation |  |  | 1,660 |  |  |  | 1,279 |
Clinical trials, outside services, and lab supplies |  |  | 26,472 |  |  |  | 23,686 |
Facilities and other |  |  | 1,817 |  |  |  | 1,962 |
Total research and development |  | $ | 36,852 |  |  | $ | 32,857 |
Selling, general and administrative: |  |  |  |  |  |
Salaries and staff costs |  | $ | 3,286 |  |  | $ | 3,531 |
Stock-based compensation |  |  | 3,100 |  |  |  | 3,230 |
Outside services and professional fees |  |  | 4,369 |  |  |  | 4,133 |
Facilities and other |  |  | 1,727 |  |  |  | 2,149 |
Total selling, general and administrative |  | $ | 12,482 |  |  | $ | 13,043 |
Useful Life of Property and Equipment | The estimated useful lives of the major classes of property and equipment are as follows:
| Estimated Useful Lives
Furniture and office equipment | 3 to 5 years
Leasehold improvements | 4 to 6 years
Laboratory equipment | 5 years
Property and equipment consisted of the following:
(in thousands) |  | As of December 31, 2024 |  |  | As of December 31, 2023 |
Furniture and office equipment |  | $ | 1,053 |  |  | $ | 1,067 |
Leasehold improvements |  |  | 2,568 |  |  |  | 2,568 |
Laboratory equipment |  |  | 1,414 |  |  |  | 1,355 |
Property and equipment, gross |  |  | 5,035 |  |  |  | 4,990 |
Less—accumulated depreciation |  |  | (4,137 | ) |  |  | (3,752 | )
Property and equipment, net |  | $ | 898 |  |  | $ | 1,238 |
Schedule of Antidilutive Securities Excluded from the Calculation of Basic and Diluted Loss Per Share | Shares used in calculating diluted net loss per common share exclude as anti-dilutive the following share equivalents:
|  | December 31, |
|  | 2024 |  |  | 2023 |
Options to purchase Common Stock |  |  | 8,334,765 |  |  |  | 6,650,954 |
Warrants to purchase Common Stock |  |  | 2,807,353 |  |  |  | 2,807,948 |
Series A Convertible Preferred Stock |  |  | 877 |  |  |  | 877 |
|  |  | 11,142,995 |  |  |  | 9,459,779 |

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