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Basis of Presentation and Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2024

Accounting Policies [Abstract]

Summary of Segment Reconciliation

		Year Ended December 31,
(in thousands)		2024				2023
Research and development:
Salaries and staff costs		$	6,903			$	5,930
Stock-based compensation			1,660				1,279
Clinical trials, outside services, and lab supplies			26,472				23,686
Facilities and other			1,817				1,962
Total research and development		$	36,852			$	32,857
Selling, general and administrative:
Salaries and staff costs		$	3,286			$	3,531
Stock-based compensation			3,100				3,230
Outside services and professional fees			4,369				4,133
Facilities and other			1,727				2,149
Total selling, general and administrative		$	12,482			$	13,043

Useful Life of Property and Equipment

The estimated useful lives of the major classes of property and equipment are as follows:

	Estimated Useful Lives
Furniture and office equipment	3 to 5 years
Leasehold improvements	4 to 6 years
Laboratory equipment	5 years

Property and equipment consisted of the following:

(in thousands)		As of December 31, 2024				As of December 31, 2023
Furniture and office equipment		$	1,053			$	1,067
Leasehold improvements			2,568				2,568
Laboratory equipment			1,414				1,355
Property and equipment, gross			5,035				4,990
Less—accumulated depreciation			(4,137	)			(3,752	)
Property and equipment, net		$	898			$	1,238

Schedule of Antidilutive Securities Excluded from the Calculation of Basic and Diluted Loss Per Share

Shares used in calculating diluted net loss per common share exclude as anti-dilutive the following share equivalents:

		December 31,
		2024				2023
Options to purchase Common Stock			8,334,765				6,650,954
Warrants to purchase Common Stock			2,807,353				2,807,948
Series A Convertible Preferred Stock			877				877
			11,142,995				9,459,779

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Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation.

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Tabular disclosure of the reconciliation of profit (loss) from reportable segments to the consolidated income (loss) before income tax expense (benefit) and discontinued operations. Includes, but is not limited to, reconciliation after income tax if income tax is allocated to the reportable segment.

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Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

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