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Stock-Based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2025
Share-Based Payment Arrangement [Abstract] |
Schedule of Stock-Based Compensation Expense | Stock-based compensation has been recognized in operating results as follows:
(in thousands) |  | Years ended December 31, |
|  | 2025 |  |  | 2024 |
Research and development expenses |  | $ | 2,376 |  |  | $ | 1,660 |
Selling, general and administrative expenses |  |  | 3,317 |  |  |  | 3,100 |
Total stock-based compensation |  | $ | 5,693 |  |  | $ | 4,760 |
Schedule of Assumptions to Estimate Fair Value of Stock Option Awards | The estimated fair value of stock option awards was determined on the date of grant using the Black-Scholes option valuation model with the following assumptions during the years indicated below:
|  | Years ended December 31,
|  | 2025 |  | 2024
Risk-free interest rate (range) |  | 3.89% - 4.11% |  | 4.04% - 4.27%
Dividend yield |  | 0% |  | 0%
Expected volatility (range) |  | 104% - 106% |  | 103% - 107%
Expected term (in years) |  | 6.2 |  | 5.8
Summary of Stock Option Activity | A summary of stock option activity and of changes in stock options outstanding is presented below:
|  | Number of Options |  |  | Weighted- Average Exercise Price Per Share |  |  | Intrinsic Value |  |  | Weighted- Average Remaining Contractual Life
Balance outstanding, December 31, 2024 |  |  | 8,334,765 |  |  | $ | 3.88 |  |  | $ | 11,668,989 |  |  | 7.5 years
Granted |  |  | 3,368,632 |  |  | $ | 3.59 |  |  |  |  |  |
Exercised |  |  | (283,065 | ) |  | $ | 1.74 |  |  | $ | 158,343 |  |  |
Forfeited |  |  | (589,583 | ) |  | $ | 2.97 |  |  |  |  |  |
Expired |  |  | (73,456 | ) |  | $ | 8.29 |  |  |  |  |  |
Balance Outstanding, December 31, 2025 |  |  | 10,757,293 |  |  | $ | 3.87 |  |  | $ | 2,678,115 |  |  | 7.1 years
Vested and exercisable, December 31, 2025 |  |  | 6,272,094 |  |  | $ | 4.22 |  |  | $ | 2,143,080 |  |  | 5.9 years
Vested and expected to vest, December 31, 2025 |  |  | 10,542,439 |  |  | $ | 3.88 |  |  | $ | 2,641,323 |  |  | 7.1 years

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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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