XML 34 R24.htm IDEA: XBRL DOCUMENT
v3.25.4

Basis of Presentation and Summary of Significant Accounting Policies (Tables) | 12 Months Ended
--- | ---
Dec. 31, 2025
Accounting Policies [Abstract] |
Summary of Segment Reconciliation | All financial information required for segment reporting that is provided to the chief operating decision-maker is contained within the financial statements and notes to financial statements, with the exception of the disaggregated amounts contained in the table below:
|  | Year Ended December 31, |
(in thousands) |  | 2025 |  |  | 2024 |
Research and development: |  |  |  |  |  |
Salaries and staff costs |  | $ | 7,131 |  |  | $ | 6,903 |
Stock-based compensation |  |  | 2,376 |  |  |  | 1,660 |
Clinical trials, outside services, and lab supplies |  |  | 23,954 |  |  |  | 26,472 |
Facilities and other |  |  | 1,868 |  |  |  | 1,817 |
Total research and development |  | $ | 35,329 |  |  | $ | 36,852 |
Selling, general and administrative: |  |  |  |  |  |
Salaries and staff costs |  | $ | 3,973 |  |  | $ | 3,286 |
Stock-based compensation |  |  | 3,317 |  |  |  | 3,100 |
Outside services and professional fees |  |  | 5,262 |  |  |  | 4,369 |
Facilities and other |  |  | 1,672 |  |  |  | 1,727 |
Total selling, general and administrative |  | $ | 14,224 |  |  | $ | 12,482 |
Useful Life of Property and Equipment | The estimated useful lives of the major classes of property and equipment are as follows:
| Estimated Useful Lives
Furniture and office equipment | 3 to 5 years
Leasehold improvements | 4 to 6 years
Laboratory equipment | 5 years
Property and equipment consisted of the following:
(in thousands) |  | As of December 31, 2025 |  |  | As of December 31, 2024 |
Furniture and office equipment |  | $ | 1,051 |  |  | $ | 1,053 |
Leasehold improvements |  |  | 2,568 |  |  |  | 2,568 |
Laboratory equipment |  |  | 1,426 |  |  |  | 1,414 |
Property and equipment, gross |  |  | 5,045 |  |  |  | 5,035 |
Less—accumulated depreciation |  |  | (4,467 | ) |  |  | (4,137 | )
Property and equipment, net |  | $ | 578 |  |  | $ | 898 |
Schedule of Antidilutive Securities Excluded from the Calculation of Diluted Net Loss per Share | Shares used in calculating diluted net loss per common share exclude as anti-dilutive the following share equivalents:
|  | December 31, |
|  | 2025 |  |  | 2024 |
Options to purchase Common Stock |  |  | 10,757,293 |  |  |  | 8,334,765 |
Warrants to purchase Common Stock |  |  | 432 |  |  |  | 2,807,353 |
Series A Convertible Preferred Stock |  |  | 877 |  |  |  | 877 |
|  |  | 10,758,602 |  |  |  | 11,142,995 |

X
- References No definition available. + Details
Name: | us-gaap_AccountingPoliciesAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 1 -SubTopic 10 -Topic 360 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482099/360-10-50-1 + Details
Name: | us-gaap_PropertyPlantAndEquipmentTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of the reconciliation of profit (loss) from reportable segments to the consolidated income (loss) before income tax expense (benefit) and discontinued operations. Includes, but is not limited to, reconciliation after income tax if income tax is allocated to the reportable segment. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 31 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-31 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
Name: | us-gaap_ReconciliationOfOperatingProfitLossFromSegmentsToConsolidatedTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482662/260-10-50-1 + Details
Name: | us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration