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Basis of Presentation and Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2025

Accounting Policies [Abstract]

Summary of Segment Reconciliation

All financial information required for segment reporting that is provided to the chief operating decision-maker is contained within the financial statements and notes to financial statements, with the exception of the disaggregated amounts contained in the table below:

		Year Ended December 31,
(in thousands)		2025				2024
Research and development:
Salaries and staff costs		$	7,131			$	6,903
Stock-based compensation			2,376				1,660
Clinical trials, outside services, and lab supplies			23,954				26,472
Facilities and other			1,868				1,817
Total research and development		$	35,329			$	36,852
Selling, general and administrative:
Salaries and staff costs		$	3,973			$	3,286
Stock-based compensation			3,317				3,100
Outside services and professional fees			5,262				4,369
Facilities and other			1,672				1,727
Total selling, general and administrative		$	14,224			$	12,482

Useful Life of Property and Equipment

The estimated useful lives of the major classes of property and equipment are as follows:

	Estimated Useful Lives
Furniture and office equipment	3 to 5 years
Leasehold improvements	4 to 6 years
Laboratory equipment	5 years

Property and equipment consisted of the following:

(in thousands)		As of December 31, 2025				As of December 31, 2024
Furniture and office equipment		$	1,051			$	1,053
Leasehold improvements			2,568				2,568
Laboratory equipment			1,426				1,414
Property and equipment, gross			5,045				5,035
Less—accumulated depreciation			(4,467	)			(4,137	)
Property and equipment, net		$	578			$	898

Schedule of Antidilutive Securities Excluded from the Calculation of Diluted Net Loss per Share

Shares used in calculating diluted net loss per common share exclude as anti-dilutive the following share equivalents:

		December 31,
		2025				2024
Options to purchase Common Stock			10,757,293				8,334,765
Warrants to purchase Common Stock			432				2,807,353
Series A Convertible Preferred Stock			877				877
			10,758,602				11,142,995

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Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation.

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-Name Accounting Standards Codification
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-SubTopic 10
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Tabular disclosure of the reconciliation of profit (loss) from reportable segments to the consolidated income (loss) before income tax expense (benefit) and discontinued operations. Includes, but is not limited to, reconciliation after income tax if income tax is allocated to the reportable segment.

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Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

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