XML 40 R30.htm IDEA: XBRL DOCUMENT v3.25.4

Income Taxes (Tables)

12 Months Ended

Dec. 31, 2025

Income Tax Disclosure [Abstract]

Schedule of Loss Before Income Taxes

The Company's loss before income taxes is as follows:

(in thousands)		Years ended December 31,
		2025				2024
U.S. Domestic		$	(45,851	)		$	(45,431	)
Loss before income taxes		$	(45,851	)		$	(45,431	)

Provision for Income Tax (Benefit) Expense

The provision for income tax (benefit) expense consists of the following:

		Years ended December 31,
(in thousands)		2025				2024
Current:
Federal		$	—			$	—
State			—				—
Total current income tax (benefit) expense			—				—
Deferred:
Federal			(8,615	)			(8,697	)
State			(213	)			(566	)
Total deferred income tax (benefit) expense			(8,828	)			(9,263	)
Valuation allowance			8,828				9,263
Total income tax (benefit) expense		$	—			$	—

Schedule of Significant Components of the Company's Taxes and the Rates

Significant components of the Company’s taxes and the rates are shown below:

		Years ended December 31,
(in thousands, except percentages)		2025								2024
US federal statutory rate		$	(9,628	)			21.0	%		$	(9,540	)			21.0	%
State and local taxes net of federal income tax effect(1)			(408	)			0.9	%			1				—	%
Tax Credits:
Research and development credits			(591	)			1.3	%			(642	)			1.4	%
Change in valuation allowance			8,615				(18.8	)%			8,816				(19.4	)%
Nontaxable or Nondeductible Items:
Officers' compensation			348				(0.7	)%			588				(1.3	)%
Stock-based compensation			432				(1.0	)%			488				(1.1	)%
Other			5				—	%			5				—	%
Other adjustments			400				(0.9	)%			284				(0.6	)%
Change in unrecognized tax benefits			827				(1.8	)%			—				—	%
Effective income tax rate		$	—				—	%		$	—				—	%

(1) Income tax rate associated with the state of California.

Schedule of Significant Components of the Company's Deferred Tax Assets and Liabilities

Significant components of the Company’s deferred tax assets and liabilities from federal and state income taxes are shown below:

		Years ended December 31,
(in thousands)		2025				2024
Deferred tax assets:
Tax loss carryforwards		$	31,977			$	27,374
Research and development credits and other tax credits			4,685				4,556
Stock-based compensation			1,645				1,252
Capitalized research and development			17,597				14,209
Operating lease liabilities			180				327
Other			1,314				967
Total deferred tax assets			57,398				48,685
Deferred tax liabilities:
Operating lease right-of-use assets			(136	)			(251	)
Total deferred tax liabilities			(136	)			(251	)
Net deferred tax assets before valuation allowance			57,262				48,434
Valuation allowance			(57,262	)			(48,434	)
Net deferred tax asset		$	—			$	—

Schedule of Changes in Valuation Allowance

A summary of changes to the Company's valuation allowance is presented below:

		Years ended December 31,
(in thousands)		2025				2024
Deferred Tax Assets - Valuation Allowance
Balance at beginning of year		$	48,434			$	39,171
Federal increase/(decrease) charge to expenses			8,615				8,816
State increase/(decrease) charge to expenses			213				447
Balance at end of year		$	57,262			$	48,434

Schedule of Unrecognized Tax Benefits

The Company's gross unrecognized tax benefits are as follows:

		Years ended December 31,
(in thousands)		2025				2024
Unrecognized tax benefits
Beginning balance		$	—			$	—
Increases related to prior year tax positions			777				—
Increases related to current year tax positions			158				—
Balance at end of year		$	935			$	—

Schedule of Cash Taxes Paid

The amounts of cash taxes paid are as follows:

(in thousands)		Years ended December 31,
		2025				2024
Current:
Federal		$	—			$	—
State:
California			1				1
Cash paid for income taxes		$	1			$	1

X

- Definition

Schedule of Cash Taxes Paid

+ References

No definition available.

+ Details

Name:	crdf_ScheduleOfCashTaxesPaidTableTextBlock
Namespace Prefix:	crdf_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- References

No definition available.

+ Details

Name:	us-gaap_IncomeTaxDisclosureAbstract
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 9
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-9

+ Details

Name:	us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-2

+ Details

Name:	us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 55
-Paragraph 231
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482663/740-10-55-231

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 12A
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-12A

Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 12
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-12

+ Details

Name:	us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of income before income tax between domestic and foreign jurisdictions.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 235
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08(h)(1)(Note 1))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480678/235-10-S99-1

+ Details

Name:	us-gaap_ScheduleOfIncomeBeforeIncomeTaxDomesticAndForeignTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the change in unrecognized tax benefits.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 55
-Paragraph 217
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482663/740-10-55-217

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 15A
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-15A

+ Details

Name:	us-gaap_ScheduleOfUnrecognizedTaxBenefitsRollForwardTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of valuation allowances to reduce deferred tax assets to net realizable value, including identification of the deferred tax asset more likely than not will not be fully realized and the corresponding amount of the valuation allowance.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (c)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-2

+ Details

Name:	us-gaap_SummaryOfValuationAllowanceTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration