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Income Taxes - Reconciliation of Federal Statutory Income Tax Rate to Effective Income Tax Rate (Details) | 12 Months Ended
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Dec. 31, 2022 | Dec. 31, 2021
Income Tax Disclosure [Abstract] |  |
Income tax computed at federal statutory rate% | 21.00% | 21.00%
State taxes, net of federal benefit | 5.60% | 5.70%
Change in valuation allowance | (26.60%) | (27.70%)
Research and development credit carryovers | 1.70% | 1.90%
Permanent differences | (1.70%) | (0.90%)
Effective income tax rate% | 0.00% | 0.00%

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