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Fair Value Measurements - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended
Jan. 31, 2022
Jan. 31, 2021
Dec. 31, 2021
Dec. 31, 2022
Level 3        
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Assets measured at fair value     $ 0 $ 0
Liabilities measured at fair value     0 0
LegoChem License Agreement        
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Derivative liability offset to research and development expenses   $ 3,400,000    
Extra milestone payment for which derivative liability recognized $ 9,600,000      
Other (Expense) Income | LegoChem License Agreement        
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Changes in the fair value of derivative liability     6,200,000  
Fair Value, Nonrecurring        
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Assets measured at fair value     0 0
Liabilities measured at fair value     $ 0 $ 0