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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Operating activities
Net loss	$ (19,243)	$ (31,380)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	190	158
Stock-based compensation	4,884	3,404
Non-cash lease expense	144	232
Accretion of discount on marketable debt securities	(607)
Changes in operating assets and liabilities:
Prepaid expenses and other assets	486	(232)
Other assets, noncurrent		(340)
Accounts payable	(753)	(9,896)
Accrued expenses and other current liabilities	(13,273)	10,540
Operating lease liabilities	1,331	(165)
Net cash used in operating activities	(26,841)	(27,679)
Investing activities
Purchase of marketable debt securities	(94,987)
Purchase of property and equipment	(4,406)	(146)
Net cash used in investing activities	(99,393)	(146)
Financing activities
Proceeds from the exercise of stock options		176
Net cash provided by financing activities		176
Net (decrease) increase in cash, cash equivalents, and restricted cash	(126,234)	(27,649)
Cash, cash equivalents and restricted cash at beginning of year	180,765	276,316
Cash, cash equivalents and restricted cash at end of period	54,531	248,667
Supplemental cash flow information:
Cash received for interest	915
Cash paid for taxes	20
Noncash investing and financing activities:
Property and equipment in accounts payable and accrued expenses	2,261
Reconciliation of cash, cash equivalents and restricted cash:
Cash and cash equivalents	53,059	247,087
Restricted cash	1,472	1,580
Total cash, cash equivalents and restricted cash shown in the statement of cash flows	$ 54,531	$ 248,667

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