<SEC-DOCUMENT>0001437749-23-024545-index.html : 20230823
<SEC-HEADER>0001437749-23-024545.hdr.sgml : 20230823
<ACCEPTANCE-DATETIME>20230823172825
ACCESSION NUMBER:		0001437749-23-024545
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20230823
DATE AS OF CHANGE:		20230823
EFFECTIVENESS DATE:		20230823

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Pyxis Oncology, Inc.
		CENTRAL INDEX KEY:			0001782223
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				831160910
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-274178
		FILM NUMBER:		231198412

	BUSINESS ADDRESS:	
		STREET 1:		321 HARRISON AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02118
		BUSINESS PHONE:		(617) 221-9059

	MAIL ADDRESS:	
		STREET 1:		321 HARRISON AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02118
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>pyxs20230817_s8.htm
<DESCRIPTION>FORM S-8
<TEXT>
Document 1 - file: pyxs20230817_s8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.5
<SEQUENCE>2
<FILENAME>ex_562251.htm
<DESCRIPTION>EXHIBIT 4.5
<TEXT>
Document 2 - file: ex_562251.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>ex_563895.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 3 - file: ex_563895.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>4
<FILENAME>ex_563855.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
Document 4 - file: ex_563855.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>5
<FILENAME>ex_563894.htm
<DESCRIPTION>EXHIBIT FILING FEES
<TEXT>
Document 5 - file: ex_563894.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>sidleylogo.jpg
<TEXT>
Document 6 - file: sidleylogo.jpg

</DOCUMENT>
</SEC-DOCUMENT>