<SEC-DOCUMENT>0001437749-23-024548-index.html : 20230823
<SEC-HEADER>0001437749-23-024548.hdr.sgml : 20230823
<ACCEPTANCE-DATETIME>20230823173008
ACCESSION NUMBER:		0001437749-23-024548
CONFORMED SUBMISSION TYPE:	S-8 POS
PUBLIC DOCUMENT COUNT:		7
FILED AS OF DATE:		20230823
DATE AS OF CHANGE:		20230823
EFFECTIVENESS DATE:		20230823

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Pyxis Oncology, Inc.
		CENTRAL INDEX KEY:			0001782223
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				831160910
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8 POS
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-272510
		FILM NUMBER:		231198433

	BUSINESS ADDRESS:	
		STREET 1:		321 HARRISON AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02118
		BUSINESS PHONE:		(617) 221-9059

	MAIL ADDRESS:	
		STREET 1:		321 HARRISON AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02118
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8 POS
<SEQUENCE>1
<FILENAME>pyxs20230816_s8pos.htm
<DESCRIPTION>FORM S-8 POS
<TEXT>
Document 1 - file: pyxs20230816_s8pos.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.3
<SEQUENCE>2
<FILENAME>ex_561711.htm
<DESCRIPTION>EXHIBIT 4.3
<TEXT>
Document 2 - file: ex_561711.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.4
<SEQUENCE>3
<FILENAME>ex_561710.htm
<DESCRIPTION>EXHIBIT 4.4
<TEXT>
Document 3 - file: ex_561710.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.5
<SEQUENCE>4
<FILENAME>ex_561712.htm
<DESCRIPTION>EXHIBIT 4.5
<TEXT>
Document 4 - file: ex_561712.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>5
<FILENAME>ex_563853.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 5 - file: ex_563853.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>6
<FILENAME>ex_563854.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
Document 6 - file: ex_563854.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>sidleylogo.jpg
<TEXT>
Document 7 - file: sidleylogo.jpg

</DOCUMENT>
</SEC-DOCUMENT>