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Proc-Type: 2001,MIC-CLEAR
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ACCESSION NUMBER:		0001119774-07-000039
CONFORMED SUBMISSION TYPE:	6-K
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20070731
FILED AS OF DATE:		20070731
DATE AS OF CHANGE:		20070731

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			COMPUGEN LTD
		CENTRAL INDEX KEY:			0001119774
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
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		STATE:			L3
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		STREET 1:		72 PINCHAS ROSEN ST
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</head>
<body lang=EN-US link=blue vlink=purple style='text-justify-trim:punctuation'>
<div class=Section1>
<p align=center  Style="margin:0cm;text-align:center;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b style='font-size:11.0pt'>FORM 6-K</b></p>
<p align=center  Style="margin:0cm;text-align:center;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b style='font-size:11.0pt'>SECURITIES AND EXCHANGE COMMISSION</b></p>
<h3 Style="text-align:center;margin-top:12.0pt;  margin-bottom:3.0pt; margin-left:0cm; page-break-after:avoid; font-size:14.0pt;  color:windowtext; font-weight:normal;font-family:"Times New Roman"" ><b style='font-size:11.0pt'>Washington</b><b style='font-size:11.0pt'>, D.C. 20549</b></h3>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b style='font-size:11.0pt'>&nbsp;</b></p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b style='font-size:11.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Report
of Foreign Private Issuer</b></p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b style='font-size:11.0pt'>&nbsp;</b></p>
<p  Style="margin:0cm;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Pursuant to rule 13a-16 or 15d-16 of the Securities
Exchange Act of 1934</p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">for the month of July 2007</p>
<p  Style="margin:0cm;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><u style='font-size:11.0pt'>Compugen Ltd.</u></p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">(Translation of registrant's name in English)</p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><u style='font-size:11.0pt'>72 Pinchas Rosen Street, Tel-Aviv 69512, Israel</u></p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">(Address of principal executive offices)</p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify: inter-ideograph;text-align:justify;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Indicate by check mark whether
the registrant files or will file annual reports under cover Form 20-F or Form
40-F.</p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Form 20-F&nbsp;&nbsp;<u> X&nbsp;&nbsp;</u>             Form
40-F&nbsp;___</p>
<p  Style="margin:0cm;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
</p>
<p  Style="margin:0cm;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify: inter-ideograph;text-align:justify;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">On July 31, 2007 Compugen Ltd.
(the &quot;Registrant&quot;) issued a Press Release, filed as Exhibit 1 to this
Report on Form 6-K, which is hereby incorporated by reference herein.</p>
<p  Style="margin:0cm;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b>&nbsp;</b></p>
<p align=center  Style="margin:0cm;text-align:center;margin-right:1.0cm;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b><u style='font-size:11.0pt'>SIGNATURE</u></b></p>
<p  Style="margin:0cm;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify: inter-ideograph;text-align:justify;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Pursuant to the requirements of
the Securities Exchange Act of 1934, the Registrant has duly caused this report
to be signed on its behalf by the undersigned, thereunto duly authorized.</p>
<p  Style="margin:0cm;margin-left:1.0cm;margin-right:1.0cm;margin-top:0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p align=center  Style="margin:0cm;text-align:center;margin-left:288.0pt;margin-right:1.0cm;margin-top:0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">                                    </p>
<p  Style="margin:0cm;text-indent:225.0pt;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Compugen Ltd.</p>
<p  Style="margin:0cm;text-indent:225.0pt;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">(Registrant)</p>
<p  Style="margin:0cm;text-indent:225.0pt;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">By:    <u>/s/ Ronit Lerner</u></p>
<p  Style="margin:0cm;text-indent:225.0pt;margin-right:1.0cm;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Title:  Chief Financial Officer</p>
<p  Style="margin:0cm;text-indent:225.0pt;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Date: July
31, 2007</p>
<p align=center  Style="margin:0cm;text-align:center;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<b style='font-size:11.0pt;font-family:"Times New Roman"'><P Style="font-size:10.0pt;font-family:"Times New Roman"" align=center><B>__1__</B>&nbsp;</P><br clear=all
style='page-break-before:always'>
</b>
<p Style="margin:0cm;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b style='font-size:11.0pt'>Exhibit 1</b></p>
<p align=center  Style="margin:0cm;text-align:center;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><img width=257
height=136 src="image001.jpg">          </p>
<h5 Style="margin:0cm;text-align:center; margin-bottom:.0001pt; page-break-after:avoid; font-size:14.0pt; color:windowtext; font-weight:bold; font-family:"Times New Roman"">Compugen Announces Discovery Engine for
Identifying Existing Drugs with Predicted New Indications</h5>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p align=center  Style="margin:0cm;text-align:center;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b><i style='font-size:11.0pt'>Nine Therapeutic Candidates Now Undergoing Validation</i></b></p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b><i style='font-size:11.0pt'>&nbsp;</i></b></p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Tel Aviv, Israel - July 31, 2007 - Compugen Ltd.
(NASDAQ: CGEN) announced today the development of a new discovery engine for
the identification of existing drug molecules that are predicted to have
important therapeutic indications that are currently not known, and the
selection of nine product candidates from the initial use of this engine.</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">The initial use of the discovery engine by Compugen
resulted in the identification of over 100 potential new therapeutic products
based on new indications for existing drugs. After applying various criteria,
including an intensive intellectual property review process, nine new
therapeutic candidates with indications that differ substantially from the
indications already approved or known for the underlying chemical entities were
selected for in vitro<i> </i>and in vivo studies. To date, three of these novel
therapeutic candidates have successfully completed in vitro screening and have
been advanced to in vivo studies. </p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">The tremendous commercial and medical value in finding
new indications for existing drugs has been well recognized by the industry for
many years. One very important advantage of this approach is that it may be
possible to advance from demonstration of efficacy in vivo directly to Phase II
clinical trials, since in many cases safety will have already been established.
For this reason, a number of companies have been very active in this area.</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Compugen`s new discovery engine analyzes an enormous
amount of information and raw data from many different experimental and drug
and disease specific sources, including gene expression from tens of thousands
of human chip experiments, known or predicted protein networks, gene regulation
data, known or predicted associations between genes and pathologies and other
experimental results. This new engine allows the integrated analysis of this
plethora of information utilizing one comprehensive computational biology
platform, thus allowing the linking of experimental results and other data and
knowledge from a great many disease areas.</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Product discovery efforts by others in this area have
focused on "drug repositioning", that is, attempts to find a possible new
indication for a specific drug. This usually involves some form of high
throughput experimentation whereby the drug of interest is screened in a
variety of different disease and/or tissue conditions. In comparison, the
Compugen <i>in silico</i> discovery platform described above is designed to
lead to the identification of those drugs predicted to have new indications
from amongst all available drugs either in commercial use or undergoing
clinical trials.</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">When desired, the Compugen approach could be directed
to find new uses for specific drugs.&nbsp;&nbsp;However, when focusing&nbsp;&nbsp;the
discovery efforts on one specific drug as in traditional drug repositioning, it
is of course extremely unlikely that this drug of interest will provide the
best - or even an acceptable - new medical and commercial opportunity -
compared with the likelihood of such an outcome when considering new
indications for any existing drug.&nbsp;&nbsp;In addition, if a new </p>
<P Style="font-size:10.0pt;font-family:"Times New Roman"" align=center><B>__2__</B>&nbsp;</P><br clear=all
style='page-break-before:always'>

<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">potential indication is identified for the drug of
interest in drug repositioning, there is no reason to expect that this specific
drug will be the best available drug for that new indication.</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Compugen`s new discovery engine is based in large part
on a recently developed computational biology platform, called MED, which
allows the integration and subsequent querying of data of multiple types and
sources. Now that this platform is available, the plan is to continue to update
it with new data as it becomes available, and then to continue to repeat new
indications discovery runs with the enhanced engine. In addition, this very
powerful and unique platform is currently being utilized in certain other
engine development programs at Compugen.</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">"As with our other programs and discovery engines -
for example our recently announced engine for discovering therapeutic
candidates for modulating GPCR`s - this new therapeutics discovery engine
replaces a largely experimental discovery process with a process consisting of <i>in
silico</i> prediction followed by experimental validation," said Yossi Cohen, M.D., Compugen`s Vice President of Research and Development. "By doing this, we
have once again shown the ability to develop platforms which make important
diagnostic and therapeutic discoveries - in this case existing drugs that are
likely to have novel indications - through a systematic and hypothesis driven
process, which I expect to get better and better with time," Dr. Cohen
concluded. </p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b style='font-size:11.0pt'>About Compugen</b></p>
<p style='margin:0cm;color:windowtext;font-size:11.0pt;margin-bottom:.0001pt;text-align:justify;text-justify: inter-ideograph'>Compugen`s
mission is to be the world leader in the discovery and licensing of product
candidates to the drug and diagnostic industry. The Company`s powerful
discovery engines enable the predictive discovery of numerous potential
therapeutics and diagnostic biomarkers. This capability results from the
Company`s decade-long pioneering efforts in the deeper understanding of
important biological phenomena at the molecular level through the incorporation
of ideas and methods from mathematics, computer science and physics into
biology, chemistry and medicine. To date, Compugen`s diagnostic and therapeutic product discovery efforts and its
initial discovery engines have focused mainly within the areas of cancer,
immune-related and cardiovascular diseases. The Company's primary commercialization
pathway for its product candidates is to enter into milestone and revenue
sharing out-licensing and joint development agreements with leading therapeutic
and diagnostic companies. Compugen has established an agricultural
biotechnology affiliate - Evogene, and a small-molecule drug discovery
affiliate - Keddem Bioscience. For additional information, please visit
Compugen's corporate Website at www.cgen.com. </p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">This press release may contain &quot;forward-looking
statements&quot; within the meaning of the Private Securities Litigation Reform
Act of 1995. These statements include words such as&nbsp;&nbsp;"may",
"expects", "anticipates", "believes", and "intends", and describe opinions
about future events. These forward-looking statements involve known and unknown
risks and uncertainties that may cause the actual results, performance or
achievements of Compugen to be materially different from any future results,
performance or achievements expressed or implied by such forward-looking
statements. Some of these risks are: changes in relationships with
collaborators; the impact of competitive products and technological changes;
risks relating to the development of new products; and the ability to implement
technological improvements. These and other factors are identified and more fully
explained under the heading &quot;Risk Factors&quot; in Compugen's annual
reports filed with the Securities and Exchange Commission.</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman""><b><i style='font-size:11.0pt'>Company contact:</i></b></p>
<h1 Style="text-justify:inter-ideograph;margin-top:3.0pt;  margin-bottom:3.0pt; margin-left:0cm; text-align:justify; page-break-after:avoid; font-size:12.0pt;  color:windowtext; font-weight:bold;font-family:"Times New Roman"" ><i style='font-size:11.0pt'>Naomi Rabbie</i></h1>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Corporate Communications Manager</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Compugen Ltd.</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Email: naomir@cgen.com</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">Tel: +972-52-598-9894</p>
<p  Style="margin:0cm;text-justify:inter-ideograph;text-align:justify;margin-bottom:.0001pt;font-size:11.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;</p>
<p  Style="margin:0cm;margin-left:241.0pt;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;<!-- Created Using Viltech Software --></p>
<p  Style="margin:0cm;margin-left:241.0pt;margin-bottom:.0001pt;font-size:10.0pt;color:windowtext;font-family:"Times New Roman"">&nbsp;<!-- Created Using Viltech Software --></p>
<P Style="font-size:10.0pt;font-family:"Times New Roman"" align=center><B>__3__</B>&nbsp;</P></div>
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`
end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----
