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SHAREHOLDERS' EQUITY (Share Option Plans) (Narrative) (Details) $ / shares in Units, $ in Thousands |  |  |  | 1 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | ---
Apr. 14, 2020 shares | Oct. 10, 2018 USD ($) $ / shares | Jun. 14, 2018 USD ($) $ / shares shares | Nov. 30, 2021 USD ($) $ / shares | Mar. 16, 2020 $ / shares shares | May 25, 2018 USD ($) $ / shares | Dec. 31, 2021 USD ($) $ / shares shares | Dec. 31, 2020 USD ($) $ / shares shares | Dec. 31, 2019 USD ($) $ / shares shares | Dec. 31, 2021 ₪ / shares | Dec. 31, 2020 ₪ / shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Weighted average fair value of stock options granted | $ / shares |  |  |  |  |  |  | $ 3.81 | $ 7.15 | $ 1.73 |  |
Unrecognized share-based compensation expense |  |  |  |  |  |  | $ 11,926 |  |  |  |
Unrecognized compensation cost, recognition period |  |  |  |  |  |  | 3 years 7 days |  |  |  |
Ordinary shares, par value | ₪ / shares |  |  |  |  |  |  |  |  |  | ₪ 0.01 | ₪ 0.01
Ordinary shares, shares authorized | shares |  |  |  |  |  |  | 200,000,000 | 200,000,000 |  |  |
Proceeds from warrant exercised |  |  |  |  |  |  | $ 425 | $ 18,325 |  |  |
Equity investment |  |  |  |  |  |  | $ 12,000 |  |  |  |
Employee Stock Purchase Plan [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Ordinary shares reserved for issuance | shares |  |  |  |  |  |  | 600,000 |  |  |  |
Ordinary shares available for issuance | shares |  |  |  |  |  |  | 482,171 |  |  |  |
Offering period |  |  |  |  |  |  | five months |  |  |  |
Percentage of use of base salary to purchase ordinary shares |  |  |  |  |  |  | 15.00% |  |  |  |
Aggregate limit of ordinary shares per calendar year | $ / shares |  |  |  |  |  |  | $ 40 |  |  |  |
Percentage of fair market value of ordinary shares at time of offering |  |  |  |  |  |  | 85.00% |  |  |  |
Options granted | shares |  |  |  |  |  |  | 117,829 |  |  |  |
Director [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Aggregate intrinsic value of exercised options |  |  |  |  |  |  | $ 759 | $ 21,610 | 979 |  |
2000 and 2010 Share Option Plans [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Ordinary shares reserved for issuance | shares |  |  |  |  |  |  | 12,395,152 |  |  |  |
Ordinary shares available for issuance | shares |  |  |  |  |  |  | 1,133,128 |  |  |  |
Vesting period |  |  |  |  |  |  | 4 years |  |  |  |
Award expiration period |  |  |  |  |  |  | 10 years |  |  |  |
Warrant [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Ordinary shares, shares authorized | shares |  |  |  |  |  |  | 3,955,696 | 3,955,696 |  |  |
Warrants purchase to ordinary shares remain outstanding | shares |  |  |  |  |  |  | 297,469 |  |  |  |
Proceeds from warrant exercised |  |  |  |  |  |  | $ 18,750 | $ 18,750 |  |  |
At The Market Offering Program [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Ordinary shares, par value | $ / shares |  |  |  |  |  | $ 0.01 |  |  |  |  |
Proceeds from issuance of common stock |  |  |  |  |  | $ 25,000 |  |  | $ 22,914 |  |
Issuance of shares, net, shares | shares |  |  |  |  |  |  |  |  | 7,245,268 |  |
Issuance expenses |  |  |  |  |  |  |  |  | $ 781 |  |
Agreement [Member] | Registered direct offering [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering price per share | $ / shares |  |  | $ 3.95 |  |  |  |  |  |  |  |
Proceeds from issuance of common stock |  |  | $ 19,767 |  |  |  |  |  |  |  |
Ordinary shares, shares authorized | shares |  |  | 5,316,457 |  |  |  |  |  |  |  |
Warrants purchase to ordinary shares | shares |  |  | 4,253,165 |  |  |  |  |  |  |  |
Exercise price of warrants | $ / shares |  |  | $ 4.74 |  |  |  |  |  |  |  |
Expiration period of warrants |  |  | 5 years |  |  |  |  |  |  |  |
Issuance expenses |  |  | $ 1,233 |  |  |  |  |  |  |  |
Master Clinical Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering price per share | $ / shares |  | $ 4.95 |  | $ 8.57333 |  |  |  |  |  |  |
Proceeds from issuance of common stock |  | $ 2,424,243 |  | $ 2,332,815 |  |  |  |  |  |  |
Equity investment |  | $ 12,000 |  | $ 20,000 |  |  |  |  |  |  |
Percentage of closing price |  | 33.00% |  | 33.00% |  |  |  |  |  |  |
Collaborative Arrangements [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of common stock |  |  |  |  |  |  | 7,788 |  |  |  |
Issuance expenses |  |  |  |  |  |  | 91 |  |  |  |
Deferred participation of BMS in R&D expenses |  |  |  |  |  |  | 4,121 |  |  |  |
Collaborative Arrangements Two [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of common stock |  |  |  |  |  |  | 14,958 |  |  |  |
Issuance expenses |  |  |  |  |  |  | 42 |  |  |  |
Deferred participation of BMS in R&D expenses |  |  |  |  |  |  | $ 5,000 |  |  |  |
SVB Leerink LLC and Stifel, Nicolaus & Company [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering price per share | $ / shares |  |  |  |  | $ 9.00 |  |  |  |  |  |
Issuance of shares, net, shares | shares |  |  |  |  | 8,333,334 |  | 8,816,339 |  |  |  |
Issuance expenses |  |  |  |  |  |  | $ 5,200 |  |  |  |
Proceeds from ordinary shares in offering |  |  |  |  |  |  | $ 74,147 |  |  |  |
SVB Leerink LLC and Stifel, Nicolaus & Company [Member] | Underwriters [Member] |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering price per share | $ / shares |  |  |  |  | $ 8.46 |  |  |  |  |  |
Issuance of shares, net, shares | shares | 483,005 |  |  |  |  |  |  |  |  |  |

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